West Coast Border Collies

DOLLY Veterinary Report by Embark embarkvet.com Test Date: June 6th, 2023 Customer-supplied information Owner Name: Joni Gibson Dog Name: Dolly Sex: Female (intact) Date of birth: n/a Breed type: purebred Breed: Border Collie Breed registration: American Border Collie Association (ABCA) Microchip: N/A Genetic summary Genetic breed identification: Border Collie Breed mix: Border Collie: 100.0% Predicted adult weight: 36 lbs Calculated from 17 size genes. Health Report How to interpret Dolly’s genetic health results: If Dolly inherited any of the variants that we tested, they will be listed at the top of the Health Report section, along with a description of how to interpret this result. We also include all of the variants that we tested Dolly for that we did not detect the risk variant for. A genetic test is not a diagnosis This genetic test does not diagnose a disease. Please talk to your vet about your dog’s genetic results, or if you think that your pet may have a health condition or disease. Summary Dolly is not at increased risk for the genetic health conditions that Embark tests. Clear results Breed-relevant (10) Other (245) Health Report BREED-RELEVANT RESULTS Research studies indicate that these results are more relevant to dogs like Dolly, and may influence her chances of developing certain health conditions. Cobalamin Malabsorption (CUBN Exon 53, Border Collie Variant) Clear Collie Eye Anomaly (NHEJ1) Clear Goniodysgenesis and Glaucoma, Pectinate Ligament Dysplasia, PLD (OLFM3) Clear MDR1 Drug Sensitivity (ABCB1) Clear Myotonia Congenita (CLCN1 Exon 23, Australian Cattle Dog Variant) Clear Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 SNP, Border Collie Variant) Clear Primary Lens Luxation (ADAMTS17) Clear Raine Syndrome (FAM20C) Clear Sensory Neuropathy (FAM134B, Border Collie Variant) Clear Trapped Neutrophil Syndrome, TNS (VPS13B) Clear Health Report OTHER RESULTS Research has not yet linked these conditions to dogs with similar breeds to Dolly. Review any increased risk or notable results to understand her potential risk and recommendations. 2-DHA Kidney & Bladder Stones (APRT) Clear Acral Mutilation Syndrome (GDNF-AS, Spaniel and Pointer Variant) Clear Alaskan Husky Encephalopathy (SLC19A3) Clear Alaskan Malamute Polyneuropathy, AMPN (NDRG1 SNP) Clear Alexander Disease (GFAP) Clear ALT Activity (GPT) Clear Anhidrotic Ectodermal Dysplasia (EDA Intron 8) Clear Autosomal Dominant Progressive Retinal Atrophy (RHO) Clear Bald Thigh Syndrome (IGFBP5) Clear Bernard-Soulier Syndrome, BSS (GP9, Cocker Spaniel Variant) Clear Bully Whippet Syndrome (MSTN) Clear Canine Elliptocytosis (SPTB Exon 30) Clear Canine Fucosidosis (FUCA1) Clear Canine Leukocyte Adhesion Deficiency Type I, CLAD I (ITGB2, Setter Variant) Clear Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant) Clear Canine Multifocal Retinopathy, cmr1 (BEST1 Exon 2) Clear Canine Multifocal Retinopathy, cmr2 (BEST1 Exon 5, Coton de Tulear Variant) Clear Canine Multifocal Retinopathy, cmr3 (BEST1 Exon 10 Deletion, Finnish and Swedish Lapphund, Lapponian Herder Variant) Clear Health Report OTHER RESULTS Canine Multiple System Degeneration (SERAC1 Exon 4, Chinese Crested Variant) Clear Canine Multiple System Degeneration (SERAC1 Exon 15, Kerry Blue Terrier Variant) Clear Cardiomyopathy and Juvenile Mortality (YARS2) Clear Centronuclear Myopathy, CNM (PTPLA) Clear Cerebellar Hypoplasia (VLDLR, Eurasier Variant) Clear Chondrodysplasia (ITGA10, Norwegian Elkhound and Karelian Bear Dog Variant) Clear Cleft Lip and/or Cleft Palate (ADAMTS20, Nova Scotia Duck Tolling Retriever Variant) Clear Cleft Palate, CP1 (DLX6 intron 2, Nova Scotia Duck Tolling Retriever Variant) Clear Cobalamin Malabsorption (CUBN Exon 8, Beagle Variant) Clear Complement 3 Deficiency, C3 Deficiency (C3) Clear Congenital Cornification Disorder (NSDHL, Chihuahua Variant) Clear Congenital Hypothyroidism (TPO, Rat, Toy, Hairless Terrier Variant) Clear Congenital Hypothyroidism (TPO, Tenterfield Terrier Variant) Clear Congenital Hypothyroidism with Goiter (TPO Intron 13, French Bulldog Variant) Clear Congenital Hypothyroidism with Goiter (SLC5A5, Shih Tzu Variant) Clear Congenital Macrothrombocytopenia (TUBB1 Exon 1, Cairn and Norfolk Terrier Variant) Clear Congenital Myasthenic Syndrome, CMS (COLQ, Labrador Retriever Variant) Clear Congenital Myasthenic Syndrome, CMS (COLQ, Golden Retriever Variant) Clear Health Report OTHER RESULTS Congenital Myasthenic Syndrome, CMS (CHAT, Old Danish Pointing Dog Variant) Clear Congenital Myasthenic Syndrome, CMS (CHRNE, Jack Russell Terrier Variant) Clear Congenital Stationary Night Blindness (LRIT3, Beagle Variant) Clear Congenital Stationary Night Blindness (RPE65, Briard Variant) Clear Craniomandibular Osteopathy, CMO (SLC37A2) Clear Craniomandibular Osteopathy, CMO (SLC37A2 Intron 16, Basset Hound Variant) Clear Cystinuria Type I-A (SLC3A1, Newfoundland Variant) Clear Cystinuria Type II-A (SLC3A1, Australian Cattle Dog Variant) Clear Cystinuria Type II-B (SLC7A9, Miniature Pinscher Variant) Clear Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant) Clear Day Blindness (CNGA3 Exon 7, German Shepherd Variant) Clear Day Blindness (CNGA3 Exon 7, Labrador Retriever Variant) Clear Day Blindness (CNGB3 Exon 6, German Shorthaired Pointer Variant) Clear Deafness and Vestibular Syndrome of Dobermans, DVDob, DINGS (MYO7A) Clear Degenerative Myelopathy, DM (SOD1A) Clear Demyelinating Polyneuropathy (SBF2/MTRM13) Clear Dental-Skeletal-Retinal Anomaly (MIA3, Cane Corso Variant) Clear Diffuse Cystic Renal Dysplasia and Hepatic Fibrosis (INPP5E Intron 9, Norwich Terrier Variant) Clear Health Report OTHER RESULTS Dilated Cardiomyopathy, DCM (RBM20, Schnauzer Variant) Clear Dilated Cardiomyopathy, DCM1 (PDK4, Doberman Pinscher Variant 1) Clear Dilated Cardiomyopathy, DCM2 (TTN, Doberman Pinscher Variant 2) Clear Disproportionate Dwarfism (PRKG2, Dogo Argentino Variant) Clear Dry Eye Curly Coat Syndrome (FAM83H Exon 5) Clear Dystrophic Epidermolysis Bullosa (COL7A1, Central Asian Shepherd Dog Variant) Clear Dystrophic Epidermolysis Bullosa (COL7A1, Golden Retriever Variant) Clear Early Bilateral Deafness (LOXHD1 Exon 38, Rottweiler Variant) Clear Early Onset Adult Deafness, EOAD (EPS8L2 Deletion, Rhodesian Ridgeback Variant) Clear Early Onset Cerebellar Ataxia (SEL1L, Finnish Hound Variant) Clear Ehlers Danlos (ADAMTS2, Doberman Pinscher Variant) Clear Enamel Hypoplasia (ENAM Deletion, Italian Greyhound Variant) Clear Enamel Hypoplasia (ENAM SNP, Parson Russell Terrier Variant) Clear Episodic Falling Syndrome (BCAN) Clear Exercise-Induced Collapse, EIC (DNM1) Clear Factor VII Deficiency (F7 Exon 5) Clear Factor XI Deficiency (F11 Exon 7, Kerry Blue Terrier Variant) Clear Familial Nephropathy (COL4A4 Exon 3, Cocker Spaniel Variant) Clear Health Report OTHER RESULTS Familial Nephropathy (COL4A4 Exon 30, English Springer Spaniel Variant) Clear Fanconi Syndrome (FAN1, Basenji Variant) Clear Fetal-Onset Neonatal Neuroaxonal Dystrophy (MFN2, Giant Schnauzer Variant) Clear Glanzmann's Thrombasthenia Type I (ITGA2B Exon 13, Great Pyrenees Variant) Clear Glanzmann's Thrombasthenia Type I (ITGA2B Exon 12, Otterhound Variant) Clear Globoid Cell Leukodystrophy, Krabbe disease (GALC Exon 5, Terrier Variant) Clear Glycogen Storage Disease Type IA, Von Gierke Disease, GSD IA (G6PC, Maltese Variant) Clear Glycogen Storage Disease Type IIIA, GSD IIIA (AGL, Curly Coated Retriever Variant) Clear Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency (PFKM, Whippet and English Springer Spaniel Variant) Clear Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency (PFKM, Wachtelhund Variant) Clear GM1 Gangliosidosis (GLB1 Exon 2, Portuguese Water Dog Variant) Clear GM1 Gangliosidosis (GLB1 Exon 15, Shiba Inu Variant) Clear GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant) Clear GM2 Gangliosidosis (HEXA, Japanese Chin Variant) Clear GM2 Gangliosidosis (HEXB, Poodle Variant) Clear Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1 (SLC4A3) Clear Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2 (TTC8) Clear Hemophilia A (F8 Exon 11, German Shepherd Variant 1) Clear Health Report OTHER RESULTS Hemophilia A (F8 Exon 1, German Shepherd Variant 2) Clear Hemophilia A (F8 Exon 10, Boxer Variant) Clear Hemophilia B (F9 Exon 7, Terrier Variant) Clear Hemophilia B (F9 Exon 7, Rhodesian Ridgeback Variant) Clear Hereditary Ataxia, Cerebellar Degeneration (RAB24, Old English Sheepdog and Gordon Setter Variant) Clear Hereditary Cataracts (HSF4 Exon 9, Australian Shepherd Variant) Clear Hereditary Footpad Hyperkeratosis (FAM83G, Terrier and Kromfohrlander Variant) Clear Hereditary Footpad Hyperkeratosis (DSG1, Rottweiler Variant) Clear Hereditary Nasal Parakeratosis (SUV39H2 Intron 4, Greyhound Variant) Clear Hereditary Nasal Parakeratosis, HNPK (SUV39H2) Clear Hereditary Vitamin D-Resistant Rickets (VDR) Clear Hypocatalasia, Acatalasemia (CAT) Clear Hypomyelination and Tremors (FNIP2, Weimaraner Variant) Clear Hypophosphatasia (ALPL Exon 9, Karelian Bear Dog Variant) Clear Ichthyosis (NIPAL4, American Bulldog Variant) Clear Ichthyosis (ASPRV1 Exon 2, German Shepherd Variant) Clear Ichthyosis (SLC27A4, Great Dane Variant) Clear Ichthyosis, Epidermolytic Hyperkeratosis (KRT10, Terrier Variant) Clear Health Report OTHER RESULTS Ichthyosis, ICH1 (PNPLA1, Golden Retriever Variant) Clear Inflammatory Myopathy (SLC25A12) Clear Inherited Myopathy of Great Danes (BIN1) Clear Inherited Selected Cobalamin Malabsorption with Proteinuria (CUBN, Komondor Variant) Clear Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12) Clear Intestinal Lipid Malabsorption (ACSL5, Australian Kelpie) Clear Junctional Epidermolysis Bullosa (LAMA3 Exon 66, Australian Cattle Dog Variant) Clear Junctional Epidermolysis Bullosa (LAMB3 Exon 11, Australian Shepherd Variant) Clear Juvenile Epilepsy (LGI2) Clear Juvenile Laryngeal Paralysis and Polyneuropathy (RAB3GAP1, Rottweiler Variant) Clear Juvenile Myoclonic Epilepsy (DIRAS1) Clear L-2-Hydroxyglutaricaciduria, L2HGA (L2HGDH, Staffordshire Bull Terrier Variant) Clear Lagotto Storage Disease (ATG4D) Clear Laryngeal Paralysis (RAPGEF6, Miniature Bull Terrier Variant) Clear Late Onset Spinocerebellar Ataxia (CAPN1) Clear Late-Onset Neuronal Ceroid Lipofuscinosis, NCL 12 (ATP13A2, Australian Cattle Dog Variant) Clear Leonberger Polyneuropathy 1 (LPN1, ARHGEF10) Clear Leonberger Polyneuropathy 2 (GJA9) Clear Health Report OTHER RESULTS Lethal Acrodermatitis, LAD (MKLN1) Clear Leukodystrophy (TSEN54 Exon 5, Standard Schnauzer Variant) Clear Ligneous Membranitis, LM (PLG) Clear Limb Girdle Muscular Dystrophy (SGCD, Boston Terrier Variant) Clear Limb-Girdle Muscular Dystrophy 2D (SGCA Exon 3, Miniature Dachshund Variant) Clear Long QT Syndrome (KCNQ1) Clear Lundehund Syndrome (LEPREL1) Clear Macular Corneal Dystrophy, MCD (CHST6) Clear Malignant Hyperthermia (RYR1) Clear May-Hegglin Anomaly (MYH9) Clear Methemoglobinemia (CYB5R3, Pit Bull Terrier Variant) Clear Methemoglobinemia (CYB5R3) Clear Microphthalmia (RBP4 Exon 2, Soft Coated Wheaten Terrier Variant) Clear Mucopolysaccharidosis IIIB, Sanfilippo Syndrome Type B, MPS IIIB (NAGLU, Schipperke Variant) Clear Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A, MPS IIIA (SGSH Exon 6, Dachshund Variant) Clear Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A, MPS IIIA (SGSH Exon 6, New Zealand Huntaway Variant) Clear Mucopolysaccharidosis Type VI, Maroteaux-Lamy Syndrome, MPS VI (ARSB Exon 5, Miniature Pinscher Variant) Clear Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant) Clear Health Report OTHER RESULTS Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 5, Terrier Brasileiro Variant) Clear Muscular Dystrophy (DMD, Cavalier King Charles Spaniel Variant 1) Clear Muscular Dystrophy (DMD, Golden Retriever Variant) Clear Musladin-Lueke Syndrome, MLS (ADAMTSL2) Clear Myasthenia Gravis-Like Syndrome (CHRNE, Heideterrier Variant) Clear Myotonia Congenita (CLCN1 Exon 7, Miniature Schnauzer Variant) Clear Narcolepsy (HCRTR2 Exon 1, Dachshund Variant) Clear Narcolepsy (HCRTR2 Intron 4, Doberman Pinscher Variant) Clear Narcolepsy (HCRTR2 Intron 6, Labrador Retriever Variant) Clear Nemaline Myopathy (NEB, American Bulldog Variant) Clear Neonatal Cerebellar Cortical Degeneration (SPTBN2, Beagle Variant) Clear Neonatal Encephalopathy with Seizures, NEWS (ATF2) Clear Neonatal Interstitial Lung Disease (LAMP3) Clear Neuroaxonal Dystrophy, NAD (VPS11, Rottweiler Variant) Clear Neuroaxonal Dystrophy, NAD (TECPR2, Spanish Water Dog Variant) Clear Neuronal Ceroid Lipofuscinosis 1, NCL 1 (PPT1 Exon 8, Dachshund Variant 1) Clear Neuronal Ceroid Lipofuscinosis 10, NCL 10 (CTSD Exon 5, American Bulldog Variant) Clear Neuronal Ceroid Lipofuscinosis 2, NCL 2 (TPP1 Exon 4, Dachshund Variant 2) Clear Health Report OTHER RESULTS Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 Deletion, Golden Retriever Variant) Clear Neuronal Ceroid Lipofuscinosis 6, NCL 6 (CLN6 Exon 7, Australian Shepherd Variant) Clear Neuronal Ceroid Lipofuscinosis 7, NCL 7 (MFSD8, Chihuahua and Chinese Crested Variant) Clear Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8, Australian Shepherd Variant) Clear Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8 Exon 2, English Setter Variant) Clear Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8 Insertion, Saluki Variant) Clear Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A (ARSG Exon 2, American Staffordshire Terrier Variant) Clear Oculocutaneous Albinism, OCA (SLC45A2 Exon 6, Bullmastiff Variant) Clear Oculocutaneous Albinism, OCA (SLC45A2, Small Breed Variant) Clear Oculoskeletal Dysplasia 2 (COL9A2, Samoyed Variant) Clear Osteochondrodysplasia (SLC13A1, Poodle Variant) Clear Osteogenesis Imperfecta (COL1A2, Beagle Variant) Clear Osteogenesis Imperfecta (SERPINH1, Dachshund Variant) Clear Osteogenesis Imperfecta (COL1A1, Golden Retriever Variant) Clear P2Y12 Receptor Platelet Disorder (P2Y12) Clear Pachyonychia Congenita (KRT16, Dogue de Bordeaux Variant) Clear Paroxysmal Dyskinesia, PxD (PIGN) Clear Persistent Mullerian Duct Syndrome, PMDS (AMHR2) Clear Health Report OTHER RESULTS Pituitary Dwarfism (POU1F1 Intron 4, Karelian Bear Dog Variant) Clear Platelet Factor X Receptor Deficiency, Scott Syndrome (TMEM16F) Clear Polycystic Kidney Disease, PKD (PKD1) Clear Pompe's Disease (GAA, Finnish and Swedish Lapphund, Lapponian Herder Variant) Clear Prekallikrein Deficiency (KLKB1 Exon 8) Clear Primary Ciliary Dyskinesia, PCD (NME5, Alaskan Malamute Variant) Clear Primary Ciliary Dyskinesia, PCD (CCDC39 Exon 3, Old English Sheepdog Variant) Clear Primary Hyperoxaluria (AGXT) Clear Primary Open Angle Glaucoma (ADAMTS17 Exon 11, Basset Fauve de Bretagne Variant) Clear Primary Open Angle Glaucoma (ADAMTS10 Exon 17, Beagle Variant) Clear Primary Open Angle Glaucoma (ADAMTS10 Exon 9, Norwegian Elkhound Variant) Clear Primary Open Angle Glaucoma and Primary Lens Luxation (ADAMTS17 Exon 2, Chinese Shar-Pei Variant) Clear Progressive Retinal Atrophy (SAG) Clear Progressive Retinal Atrophy (IFT122 Exon 26, Lapponian Herder Variant) Clear Progressive Retinal Atrophy, Bardet-Biedl Syndrome (BBS2 Exon 11, Shetland Sheepdog Variant) Clear Progressive Retinal Atrophy, CNGA (CNGA1 Exon 9) Clear Progressive Retinal Atrophy, crd1 (PDE6B, American Staffordshire Terrier Variant) Clear Progressive Retinal Atrophy, crd4/cord1 (RPGRIP1) Clear Health Report OTHER RESULTS Progressive Retinal Atrophy, PRA1 (CNGB1) Clear Progressive Retinal Atrophy, PRA3 (FAM161A) Clear Progressive Retinal Atrophy, prcd (PRCD Exon 1) Clear Progressive Retinal Atrophy, rcd1 (PDE6B Exon 21, Irish Setter Variant) Clear Progressive Retinal Atrophy, rcd3 (PDE6A) Clear Proportionate Dwarfism (GH1 Exon 5, Chihuahua Variant) Clear Protein Losing Nephropathy, PLN (NPHS1) Clear Pyruvate Dehydrogenase Deficiency (PDP1, Spaniel Variant) Clear Pyruvate Kinase Deficiency (PKLR Exon 5, Basenji Variant) Clear Pyruvate Kinase Deficiency (PKLR Exon 7, Beagle Variant) Clear Pyruvate Kinase Deficiency (PKLR Exon 10, Terrier Variant) Clear Pyruvate Kinase Deficiency (PKLR Exon 7, Labrador Retriever Variant) Clear Pyruvate Kinase Deficiency (PKLR Exon 7, Pug Variant) Clear Recurrent Inflammatory Pulmonary Disease, RIPD (AKNA, Rough Collie Variant) Clear Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7) Clear Retina Dysplasia and/or Optic Nerve Hypoplasia (SIX6 Exon 1, Golden Retriever Variant) Clear Severe Combined Immunodeficiency, SCID (PRKDC, Terrier Variant) Clear Severe Combined Immunodeficiency, SCID (RAG1, Wetterhoun Variant) Clear Health Report OTHER RESULTS Shaking Puppy Syndrome (PLP1, English Springer Spaniel Variant) Clear Shar-Pei Autoinflammatory Disease, SPAID, Shar-Pei Fever (MTBP) Clear Skeletal Dysplasia 2, SD2 (COL11A2, Labrador Retriever Variant) Clear Skin Fragility Syndrome (PKP1, Chesapeake Bay Retriever Variant) Clear Spinocerebellar Ataxia (SCN8A, Alpine Dachsbracke Variant) Clear Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10) Clear Spongy Degeneration with Cerebellar Ataxia 1 (KCNJ10) Clear Spongy Degeneration with Cerebellar Ataxia 2 (ATP1B2) Clear Stargardt Disease (ABCA4 Exon 28, Labrador Retriever Variant) Clear Succinic Semialdehyde Dehydrogenase Deficiency (ALDH5A1 Exon 7, Saluki Variant) Clear Thrombopathia (RASGRP1 Exon 5, American Eskimo Dog Variant) Clear Thrombopathia (RASGRP1 Exon 5, Basset Hound Variant) Clear Thrombopathia (RASGRP1 Exon 8, Landseer Variant) Clear Ullrich-like Congenital Muscular Dystrophy (COL6A3 Exon 10, Labrador Retriever Variant) Clear Ullrich-like Congenital Muscular Dystrophy (COL6A1 Exon 3, Landseer Variant) Clear Unilateral Deafness and Vestibular Syndrome (PTPRQ Exon 39, Doberman Pinscher) Clear Urate Kidney & Bladder Stones (SLC2A9) Clear Von Willebrand Disease Type I, Type I vWD (VWF) Clear Health Report OTHER RESULTS Von Willebrand Disease Type II, Type II vWD (VWF, Pointer Variant) Clear Von Willebrand Disease Type III, Type III vWD (VWF Exon 4, Terrier Variant) Clear Von Willebrand Disease Type III, Type III vWD (VWF Intron 16, Nederlandse Kooikerhondje Variant) Clear Von Willebrand Disease Type III, Type III vWD (VWF Exon 7, Shetland Sheepdog Variant) Clear X-Linked Hereditary Nephropathy, XLHN (COL4A5 Exon 35, Samoyed Variant 2) Clear X-Linked Myotubular Myopathy (MTM1, Labrador Retriever Variant) Clear X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR) Clear X-linked Severe Combined Immunodeficiency, X-SCID (IL2RG Exon 1, Basset Hound Variant) Clear X-linked Severe Combined Immunodeficiency, X-SCID (IL2RG, Corgi Variant) Clear Xanthine Urolithiasis (XDH, Mixed Breed Variant) Clear β-Mannosidosis (MANBA Exon 16, Mixed-Breed Variant) Clear Mast Cell Tumor No result Genetic Diversity and Inbreeding Coefficient of Inbreeding (COI) Genetic Result: 19% Our genetic COI measures the proportion of your dog’s genome (her genes) where the genes on the mother’s side are identical by descent to those on the father’s side. The higher your dog’s coefficient of inbreeding (the percentage), the more inbred your dog is. Your Dog’s COI Coefficient of inbreeding chart This graph represents where your dog’s inbreeding levels fall on a scale compared to both dogs with a similar breed makeup to her (the blue bars) and all purebred dogs (the grey line). Genetic