40+ Mastiff puppies for sale from ethical breeders near Myrtle Beach, SC
Dakota, mom
Raised by Kim R.
Titan Mastiffs · 82 miles away from Myrtle Beach, SC
We raise our puppies with total care and attention so they can become well-socialized and loving additions to their forever homes.
1 owner review
Giorgio, dad
Brick, dad
Raised by Lucy S.
ScottsCreek Mastiffs · 83 miles away from Myrtle Beach, SC
We work hard to produce healthy, well-rounded Mastiff puppies that will make others as happy as our dogs have made us!
Zoe, mom
Raised by Cindy R.
Halfway Creek Farms · 91 miles away from Myrtle Beach, SC
I raise Mastiffs with health, care, and temperament in mind, and am part of Good Dog's vetted network.
Tric, dad
Mia, mom
Raised by Jennifer G.
Jennifer s Appalachian Mountain Mastiffs · 143 miles away from Myrtle Beach, SC
We understand the responsibility of purposefully breeding in order to do better for the breed and the families that love them!
We’ve screened nearly every breeder in the U.S.—only 1 in 5 meet our standard for responsible breeding.
Male, reserved
Male, reserved
Raised by Katie B.
Sunrise Mastiffs · 178 miles away from Myrtle Beach, SC
We’re a small, family oriented breeding program that focuses on exceptional temperament & health.
Male, available
Female, available
Raised by Danielle P.
Little Mountain Mastiffs · 183 miles away from Myrtle Beach, SC
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
1 owner review
Sibby, mom
Grantham, dad
GSRaised by Gary S.
Two Ponds Mastiffs · 188 miles away from Myrtle Beach, SC
We here at Two Ponds Mastiffs have been raising and loving mastiffs for nearly 30 years.
Raised by Karen L.
Looking Glass English Mastiffs · 214 miles away from Myrtle Beach, SC
We absolutely love Mastiffs, and we aim to produce healthy and exceptional puppies that will thrive in their future homes.
Zeus, dad
Hera, mom
CBRaised by Chandler B.
Old Moonshine Mastiffs · 235 miles away from Myrtle Beach, SC
We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.
Male, reserved
Female, reserved
Raised by Jeana F.
Jeana's Rottweilers & English Mastiffs · 245 miles away from Myrtle Beach, SC
We work hard to produce healthy, well-rounded purebreds. Rottweiler & Mastiff puppies!
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Sterling, dad
Indy, mom
Raised by Becky C.
Coopers Mastiffs & Duck Tollers · Drop-off to you
We built our program with care and intention in every step. We care deeply about the health and wellbeing of these breeds.
NALA, mom
DMRaised by Domenic M.
Hooligan Mastiffs · Drop-off to you
We hold ourselves to high standards for the integrity of our program. All of our puppies are socialized, nurtured, and loved!
1 owner review
Male, reserved
Male, reserved
Raised by Karen W.
Lakeside English Mastiffs of Georgia and North Carolina · Drop-off to you
Our high-quality puppies are the result of extensive research and thorough care for our outstanding dogs and puppies.
1 owner review
Dakota or Kota, dad
Esther, mom
Raised by Suzie F.
Celtic's Mastiffs · Meet breeder for pickup
I've had the honor to be owned by Mastiffs I've bred for many, many years. I can't imagine my life without them by my side.
Willow, mom
Sara, mom
Raised by Candy P.
Southern Oaks Kennel · Meet breeder for pickup
Our goal is to raise healthy, happy puppies to the breed standard for families to love and enjoy as pets or for show homes.
1 owner review
Samson, dad
Raised by David H.
Hillside Mastiffs · Meet breeder for pickup
We breed high-quality mastiff/Great Dane puppies. We love what we do and are committed to producing well-bred, healthy puppies.
Bjorn, mom
Fenris, mom
Raised by Lacy S.
Storytime Mastiffs & Bulldogs · Drop-off to you
At Storytime Mastiffs & Bulldogs we pride ourselves on breeding healthy puppies while also focusing on type and temperament.
Raised by Kimberly H.
Impeccable's Boutique & Ethical Breeder for the educated & discriminating ONLY · Meet breeder for pickup
Distinctive & Healthy AKC puppies for the educated, responsible & loving companion homes. Preferred 5 Star breeder w/ references.
7 owner reviews
VALOR, dad
Olympia, mom
Raised by Julie W.
Majestic Mastiffs of Florida · Drop-off to you
We offer high-quality English Mastiffs of exceptional temperament, longevity, and type with love & pride to qualified homes.
- SB
Raised by Sue B.
Sue Blickenstaff's Mastiffs · Meet breeder for pickup
Our puppies are raised in our home. We put a lot of effort into socializing and caring for our top-quality Mastiff puppies.
Zakk, dad
Annie, mom
Raised by Carol S.
Sims English Mastiffs · Meet breeder for pickup
Show/Owner AKC 15 yrs. Retired now Stud Owner to provide healthy Purebreds from my line Sires. I have a pick pup as Stud exchg
Boogieman, dad
Zena, mom
Raised by Brian J.
MLJ Mastiffs Florida · Drop-off to you
We breed to enhance the breed with quality bone structure for size and genetics for health. We take great pride in our work!
Male, reserved
Male, reserved
Raised by Reva T.
❤️ Thompson's Family Mastiffs ❤️ · Drop-off to you
We’re proud of the healthy, affectionate, and well-rounded puppies that we produce and raise so that others may know their love.
3 owner reviews
Raised by Angela C.
Sovereign Mastiffs · Meet breeder for pickup
We responsibly breed, raise, & socialize healthy pups so others can enjoy the gift of living life with a Mastiff!
Raised by Diane G.
Sylvan Mastiffs · Meet breeder for pickup
Being a breeder is my passion, not my job. I love having the opportunity to share these wonderful companions with other families!
- LL
Raised by Lorie L.
Earth Shaking Mastiffs · Meet breeder for pickup
We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!
Nikko, dad
Zara, mom
MSRaised by Michelle S.
Beauclerc Mastiffs · Meet breeder for pickup
All of our puppies are bred, raised, and loved indoors to produce happy, healthy pets for those seeking the best family companion!
- MD
Raised by Maria D.
Warlords Mastiffs · Meet breeder for pickup
It is our goal to help ensure the future of the Mastiff through responsibly breeding our exceptional dogs.
Rosie, mom
Raised by Tim D.
Treasure Coast Mastiffs · Drop-off to you
We work hard to produce healthy, well-rounded Mastiff puppies that will make others as happy as our dogs have made us!
Apollo, dad
Roxie, mom
Raised by Maria B.
Stoneheart Mastiffs · Meet breeder for pickup
We do health testing and keep our dogs in tip top shape. They get expert vet care, great nutrition, and lots of love.
2 owner reviews
Raised by Celeste G.
Liberty Mountain · Drop-off to you
We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.
Harper, mom- Harper, mom
HMRaised by Holly M.
North Star Mastiffs · Drop-off to you
We breed and show top-quality dogs. Our heavy involvement in the show world speaks to the standards that we breed our dogs by.
Fiona, mom
Handsome, dad
Raised by Chantelle Y.
Silver Mountain Mastiffs · Meet breeder for pickup
We are strong advocates of proper breeding practices and run our program accordingly. We breed top-quality Mastiffs.
Kemper, dad
Shadow, mom
Raised by Colleen L.
Round Town Mastiffs · Meet breeder for pickup
We're new breeders starting a small program. We hope to help provide families with quality puppies as we continue to learn & grow!
Male, reserved
Sissy, mom
Raised by Peter M.
Peter Moser's Mastiffs · Meet breeder for pickup
We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.
Artemis, mom
Raised by Monica B.
Hickory Creek Mastiffs · Drop-off to you
We breed fully health tested, AKC championed Mastiffs that represent the breed standard in appearance, structure, and temperament.
Amari, mom
Howie, dad
SCRaised by Sarah C.
SMC Mastiffs / Muddy Boots Cocker Spaniels and Cockapoos · Meet breeder for pickup
We breed quality health tested dogs that have excellent temperaments. Our goal is to produce amazing family members!!
Female, reserved
Raised by Angela A.
Angela's Mastiffs · Drop-off to you
We have both AKC and CKC registered English Mastiffs and we are now also breeding the Daniff. The best of both giant breeds!
6 owner reviews
Kia, mom
Raised by Lori C.
J and L Farms Mastiff’s · Drop-off to you
We offer AKC Championship Bloodline English Mastiffs we focus on healthy well breed dogs with good temperaments.
Watcher, mom
Darth, dad
ESRaised by Erin S.
Kasota Farm · Drop-off to you
Our dogs are bred for health, temperament, and ability. We strive to produce beautiful and versatile beloved companions.
Raised by Justine C.
Murphy's Landing Mastiffs · Meet breeder for pickup
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
Raised by Becky W.
Large Paw Masiffs · Meet breeder for pickup
Our Mastiff pups are home-raised. We put a lot of care into socializing them so they can transition easily into their new lives.
Related breeds
Mastiff
Buyer’s Guide
Nationally, prices usually range from $2,500 to $3,500. While it may cost more up front, starting with a healthy puppy can help you avoid costly issues later. These ranges reflect the care behind responsible breeding and offer a reliable view of what ethical breeding really costs.
About the Mastiff
The Mastiff is an ancient breed that is well-mannered and fearless. With proper socialization, this massive breed is a noble and calm companion.
Moderate energy
Energy level
Easy coat care
Coat care
High shedding
Shedding
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Frequently asked questions
What is the average cost of Mastiff puppies in Myrtle Beach, SC?
Prices may vary based on the breeder and individual puppy for sale in Myrtle Beach, SC. On Good Dog, Mastiff puppies in Myrtle Beach, SC range in price from $2,900 to $3,400. We recommend speaking directly with your breeder to get a better idea of their price range.
Do Mastiff puppies in Myrtle Beach, SC shed?
Mastiff puppies in Myrtle Beach, SC are a high shedding breed. However, it's possible that a dog's level of shedding may vary by individual puppy.
What is the average size range of Mastiff puppies in Myrtle Beach, SC?
The expected weight range for male Mastiff puppies in Myrtle Beach, SC is 160 to 230 pounds. The expected weight range for female Mastiff puppies in Myrtle Beach, SC is 120 to 170 pounds. Because size and weight may vary based on individual dogs, your dog may be outside of that range.
What is the average lifespan for Mastiff puppies in Myrtle Beach, SC?
The average lifespan for Mastiff puppies in Myrtle Beach, SC is 6 to 10 years of age.
Can I adopt a Mastiff from a rescue or shelter?
On Good Dog, you can search for Mastiff puppies or dogs in rescues and shelters near Myrtle Beach, SC. Adopting a Mastiff from a shelter or rescue in Myrtle Beach, SC is generally less expensive than buying a puppy from a breeder with ethical practices. Across the United States, there are dedicated rescues that specialize in specific breeds and may even help transport a Mastiff dog to you in Myrtle Beach, SC from another part of the country. Although it can be more cost-effective, adopting the exact breed you're looking for is typically more difficult than working with a responsible breeder. Learn more about adopting a dog from a shelter or rescue.
About Good Dog
About Good Dog
Good Dog is your trusted partner for finding Mastiff puppies for sale near Myrtle Beach, SC. Our vetted network of responsible Mastiff breeders makes it easy to search listings, connect directly, and ask questions — all in one safe, protected place. Work directly with breeders you can trust and complete payments securely through Good Dog, so you can bring home your Mastiff puppy with confidence.