40+ Mastiff puppies for sale from ethical breeders near St. Charles, MO
Kaia, mom
Raised by Madison O.
M&M Aussie's & Mastiff's · 73 miles away from St. Charles, MO
Faceb page with more information! M&M Aussies Of Monroe City ( trying to change the name since moved and added mastiffs)
Booker, mom
Raised by Shari S.
Bowtied Lickers · 139 miles away from St. Charles, MO
We focus on intentional breeding so that we can produce quality puppies that are excellent representations of the standard.
King, mom
TPRaised by Theresa P.
Theresa's Mastiffs · 140 miles away from St. Charles, MO
We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.
- DC
Raised by David C.
David's Mastiffs · 140 miles away from St. Charles, MO
We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.
We’ve screened nearly every breeder in the U.S.—only 1 in 5 meet our standard for responsible breeding.
Tyson, dad
Alisha, mom
GSRaised by Gary G. S.
Gary Schneider’s Mastiffs · 171 miles away from St. Charles, MO
Our dogs and pups are raised in our home and are loved as family. We strive to produce high-quality show prospects and companions.
Dora, mom
Boomer, dad
Raised by Tim S.
Ozark Mountain Mastiffs · 173 miles away from St. Charles, MO
We are a small scale breeder who focuses on Mastiffs only.
25 owner reviews
Female, available
Female, available
Raised by Karin C.
Hug-A-Mug Mastiffs · 177 miles away from St. Charles, MO
I'm a preservationist breeder and passionate about the English Mastiff. I've been showing and breeding healthy litters since 1978.
Male, reserved
Female, reserved
Raised by Elizabeth R.
Riggins Mastiffs and Danes · 180 miles away from St. Charles, MO
We’re devoted to ensuring there are healthy Mastiffs for others to enjoy by responsibly growing this incredible breed.
Raised by Alison R.
AKA Shih Tzu · 201 miles away from St. Charles, MO
My program is built upon a foundation of love, admiration, and respect for the Shih Tzu and Mastiff breeds.
Raised by Caleb W.
Ozark Mountain Mastiffs · 204 miles away from St. Charles, MO
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
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Minni, mom
Raised by Michele & Andy P.
Parbury Place Mastiffs · 216 miles away from St. Charles, MO
We love the mellow temperament of these gentle giants and are excited to help other families find the perfect pup for their home.
Juno, mom
Raised by Carolyn W.
Nytewind Mastiffs · 222 miles away from St. Charles, MO
I breed Mastiffs to improve the quality of the breed and to offer service dogs to people like myself. I love my dogs & what I do!
Page, mom
Page, mom
Raised by Cathy I.
Cedarhills · 226 miles away from St. Charles, MO
We offer top quality pups to loving homes
1 owner review
Male, reserved
Female, reserved
Raised by Elesha P.
Mama’s Mastiffs · 236 miles away from St. Charles, MO
Specializing in quality, DNA health tested, OFA certified English Mastiffs since 2006
4 owner reviews
Kato, dad
Susie, mom
Raised by Kristi L.
Kentucky Mastiffs · Meet breeder for pickup
I offer top-quality Mastiff puppies for families who share the same love and passion that I do for these lovely companions.
Zucci, mom
Zuko, dad
JCRaised by Jordan C.
Big Z English Mastiff · Meet breeder for pickup
As conscientious breeders, we are proud of the loving, smart, beautiful, and sound puppies we’re able to provide for others.
Dolly, mom
Raised by JOSEPH T.
Trindade Mastiffs · Meet breeder for pickup
We are a small family breeder focused on bettering the mastiff breed.
Carmella, mom
Ginger, mom
Raised by Candie K.
Faith Mastiffs · Drop-off to you
We value responsible breeding practices and want to do our part to ensure the Mastiff will continue to thrive.
Male, reserved
Female, reserved
Raised by Karen P.
Kharisma Mastiffs · Meet breeder for pickup
Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.
BARBIE, mom
Raised by Diana B.
Puppy Paradise: English Mastiff Puppies & Standard Goldendoodle Puppies · Meet 223 miles away from St. Charles, MO
Our dogs are our beloved companions. We love to raise our puppies so they have the tools to be well-rounded, loved family members.
1 owner review
Lady, mom
Obama, dad
Raised by Alison B.
Eagle Mastiffs · Meet breeder for pickup
Our mission is to raise healthy, happy, adorable Mastiff puppies and connect loving families with their new best friend!
1 owner review
Female, available
Female, available
Raised by Jazz W.
FrontlineK9 Boarding & Training LLC · Drop-off to you
All our dogs are bred with the standard of bettering the overall health of the breed and to create a healthy reliable Mastiffs.
Raised by Diane G.
Sylvan Mastiffs · Meet breeder for pickup
Being a breeder is my passion, not my job. I love having the opportunity to share these wonderful companions with other families!
Raised by Celeste G.
Liberty Mountain · Drop-off to you
We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.
- DL
Raised by Deborah L. Hatch L.
Deborah's Mastiffs · Meet breeder for pickup
We care deeply about the Mastiff, and we breed to help ensure the health and future of these wonderful dogs.
Male, reserved
Male, reserved
Raised by Tim L.
Flanders Kennels LLC · Drop-off to you
Small, nonprofit breeder of health tested, working farmstead Boerboels and companion Mastiffs. Also help giant breed dogs in need.
Male, reserved
Duchess, mom
Raised by Legendary M.
Legendary Mastiffs · Drop-off to you
We strive to produce outstanding puppies. Our main priorities are health and temperament, and we focus on quality over quantity!
Darth, dad
Watcher, mom
ESRaised by Erin S.
Kasota Farm · Drop-off to you
Our dogs are bred for health, temperament, and ability. We strive to produce beautiful and versatile beloved companions.
Jax, dad
Marley, dad
SCRaised by Sarah C.
SMC Mastiffs / Muddy Boots Cocker Spaniels and Cockapoos · Meet 242 miles away from St. Charles, MO
We breed quality health tested dogs that have excellent temperaments. Our goal is to produce amazing family members!!
Raised by Angela C.
Sovereign Mastiffs · Meet breeder for pickup
We responsibly breed, raise, & socialize healthy pups so others can enjoy the gift of living life with a Mastiff!
Male, reserved
Male, reserved
Raised by Jeanne C.
J & J Legacy Mastiffs · Drop-off to you
We raise our dogs with love in our home. We have high expectations for our pups and strive to put each one into a loving family.
- AM
Raised by Amy M.
Whiskey Bain Mastiffs · Meet breeder for pickup
We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.
- LK
Raised by Lisa K.
Lisa Kellogg's Mastiffs · Meet breeder for pickup
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
Kia, mom
Raised by Lori C.
J and L Farms Mastiff’s · Drop-off to you
We offer AKC Championship Bloodline English Mastiffs we focus on healthy well breed dogs with good temperaments.
- LF
Raised by Leah F.
Cub Lake Pyrenees Mastiff · Meet breeder for pickup
Our family provides your family with extremely well tempered and a very healthy puppy! Each puppy goes home with a puppy care bag.
Female, reserved
KSRaised by Kati S.
4Arrows Mastiffs · Meet breeder for pickup
We raise puppies out for health tested parents who not only meet confirmation guidelines but also have temperaments to match.
- AD
Raised by Angela D.
Bittersweet Lane Mastiffs · Meet breeder for pickup
We offer high-quality Mastiff puppies to show and companion homes. We breed for health, temperament, and conformation.
Riley, mom
Grisha, mom
Raised by Julie A.
Beaver Creek Mastiffs · Drop-off to you
Our Mastiffs are raised with lots of love and pride. Making sure we provide you with the absolute best Mastiff puppy available.
Samson, dad
Raised by David H.
Hillside Mastiffs · Meet breeder for pickup
We breed high-quality mastiff/Great Dane puppies. We love what we do and are committed to producing well-bred, healthy puppies.
Fenris, mom
Knuckles, mom
Raised by Lacy S.
Storytime Mastiffs & Bulldogs · Drop-off to you
At Storytime Mastiffs & Bulldogs we pride ourselves on breeding healthy puppies while also focusing on type and temperament.
Raised by Justine C.
Murphy's Landing Mastiffs · Meet breeder for pickup
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
Raised by Becky W.
Large Paw Masiffs · Meet breeder for pickup
Our Mastiff pups are home-raised. We put a lot of care into socializing them so they can transition easily into their new lives.
Related breeds
Mastiff
Buyer’s Guide
Nationally, prices usually range from $2,500 to $3,500. While it may cost more up front, starting with a healthy puppy can help you avoid costly issues later. These ranges reflect the care behind responsible breeding and offer a reliable view of what ethical breeding really costs.
About the Mastiff
The Mastiff is an ancient breed that is well-mannered and fearless. With proper socialization, this massive breed is a noble and calm companion.
Moderate energy
Energy level
Easy coat care
Coat care
High shedding
Shedding
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Frequently asked questions
What is the average cost of Mastiff puppies in St. Charles, MO?
Prices may vary based on the breeder and individual puppy for sale in St. Charles, MO. On Good Dog, Mastiff puppies in St. Charles, MO range in price from $1,850 to $4,250. We recommend speaking directly with your breeder to get a better idea of their price range.
Do Mastiff puppies in St. Charles, MO shed?
Mastiff puppies in St. Charles, MO are a high shedding breed. However, it's possible that a dog's level of shedding may vary by individual puppy.
What is the average size range of Mastiff puppies in St. Charles, MO?
The expected weight range for male Mastiff puppies in St. Charles, MO is 160 to 230 pounds. The expected weight range for female Mastiff puppies in St. Charles, MO is 120 to 170 pounds. Because size and weight may vary based on individual dogs, your dog may be outside of that range.
What is the average lifespan for Mastiff puppies in St. Charles, MO?
The average lifespan for Mastiff puppies in St. Charles, MO is 6 to 10 years of age.
Can I adopt a Mastiff from a rescue or shelter?
On Good Dog, you can search for Mastiff puppies or dogs in rescues and shelters near St. Charles, MO. Adopting a Mastiff from a shelter or rescue in St. Charles, MO is generally less expensive than buying a puppy from a breeder with ethical practices. Across the United States, there are dedicated rescues that specialize in specific breeds and may even help transport a Mastiff dog to you in St. Charles, MO from another part of the country. Although it can be more cost-effective, adopting the exact breed you're looking for is typically more difficult than working with a responsible breeder. Learn more about adopting a dog from a shelter or rescue.
About Good Dog
About Good Dog
Good Dog is your trusted partner for finding Mastiff puppies for sale near St. Charles, MO. Our vetted network of responsible Mastiff breeders makes it easy to search listings, connect directly, and ask questions — all in one safe, protected place. Work directly with breeders you can trust and complete payments securely through Good Dog, so you can bring home your Mastiff puppy with confidence.