40+ Mastiff puppies for sale from ethical breeders near Cape Girardeau, MO

MH

Raised by Mary H.

Mary Ham's Mastiffs · Meet breeder for pickup

We are proud to offer our beautiful Mastiff puppies to loving homes! Our dogs are healthy and have great temperaments.

Raised by Monica B.

Hickory Creek Mastiffs · Drop-off to you

We breed fully health tested, AKC championed Mastiffs that represent the breed standard in appearance, structure, and temperament.

Raised by Amber W.

Weiler’s Gentle Giants · Drop-off to you

We hold ourselves to the highest standard when it comes to our dogs and our policies. We take responsible breeding very seriously.

Raised by Karen L.

Looking Glass English Mastiffs · Meet breeder for pickup

We absolutely love Mastiffs, and we aim to produce healthy and exceptional puppies that will thrive in their future homes.

Raised by Jennifer T.

Mastiffs of Middle Earth · Meet breeder for pickup

We provide quality, healthy Mastiff puppies for special families.

Raised by Emma S.

King’s Peak Kennels · Drop-off to you

I offer quality-bred puppies for Mastiff enthusiasts. I strive to improve the breed and focus on conformation in my program.

Raised by Jeanne C.

J & J Legacy Mastiffs · Drop-off to you

We raise our dogs with love in our home. We have high expectations for our pups and strive to put each one into a loving family.

AM

Raised by Amy M.

Whiskey Bain Mastiffs · Meet breeder for pickup

We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.

LK

Raised by Lisa K.

Lisa Kellogg's Mastiffs · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

CL

Raised by Cynthia L.

Luper’s Country Critters · Meet breeder for pickup

Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.

Raised by Reva T.

❤️ Thompson's Family Mastiffs ❤️ · Drop-off to you

We’re proud of the healthy, affectionate, and well-rounded puppies that we produce and raise so that others may know their love.

Raised by Mark S.

Eagle Pond Mastiffs · Meet breeder for pickup

Sire & Dam are OFA-AKC Registered & English Mastiff family lineage. DECLAWS REMOVED AFTER BIRTH. Excellent breed of Gentle Giant.

GS

Raised by Gary S.

Two Ponds Mastiffs · Meet breeder for pickup

We here at Two Ponds Mastiffs have been raising and loving mastiffs for nearly 30 years.

SD

Raised by Sherry D.

Sherwood Mastiffs · Drop-off to you

We offer high-quality puppies. Our dogs are excellent representations of their breeds, and we are proud to continue their lines.

Raised by Katie B.

Sunrise Mastiffs · Drop-off to you

We’re a small, family oriented breeding program that focuses on exceptional temperament & health.

KS

Raised by Kati S.

4Arrows Mastiffs · Meet breeder for pickup

We raise puppies out for health tested parents who not only meet confirmation guidelines but also have temperaments to match.

Raised by Danielle P.

Little Mountain Mastiffs · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Sandy H.

Red River Mastiff · Drop-off to you

We have AKC registered, family raised, loving, sweet temperaments, healthy English Mastiffs.

Raised by Dustin R.

Mastiffs of Bowdil · Drop-off to you

We strive to produce well socialized, family friendly puppies through responsible breeding to AKC standards.

Raised by Regina H.

Lone Star Legends Mastiffs · Drop-off to you

I offer top-quality Mastiff puppies for families who share the same love and passion that I do for these lovely companions.

Raised by Ashley H.

Rahas Mastiffs · Drop-off to you

I breed for the betterment of the breed. Health is my top priority, along with soundness, and temperament.

TR

Raised by Taresa R.

Taresa's Pups · Meet breeder for pickup

We are proud to offer our wonderful puppies to loving homes! Our dogs are healthy and have great temperaments.

Raised by Kacey P.

Great Lakes Mastiffs · Meet breeder for pickup

It is our goal to produce adorable, affectionate Mastiff puppies that are healthy, well-tempered, and make wonderful companions.

MD

Raised by Melissa D.

Delamar Mastiffs · Meet breeder for pickup

We’re proud of the healthy, affectionate, and behaviorally well-rounded puppies we raise for other families to love!

Raised by Brian J.

MLJ Mastiffs Florida · Drop-off to you

We breed to enhance the breed with quality bone structure for size and genetics for health. We take great pride in our work!

Raised by Chantelle Y.

Silver Mountain Mastiffs · Meet breeder for pickup

We are strong advocates of proper breeding practices and run our program accordingly. We breed top-quality Mastiffs.

LA

Raised by Lisa A.

Lisa Armstrong · Meet breeder for pickup

We are professional handlers of Mastiffs. It is our goal to produce healthy, show-quality puppies with wonderful temperaments.

Raised by Shannon R.

Lone Star Mastiff · Drop-off to you

We care deeply about Mastiffs and have built that love and respect for the breed into every aspect of our program.

Raised by Jeana F.

Jeana's Rottweilers & English Mastiffs · Drop-off to you

We work hard to produce healthy, well-rounded purebreds. Rottweiler & Mastiff puppies!

VH

Raised by Vicki H.

Twin Cities Mastiffs · Meet breeder for pickup

We are proud to offer our beautiful Mastiff puppies to loving homes! Our dogs are healthy and have great temperaments.

Raised by Candy P.

Southern Oaks Kennel · Meet breeder for pickup

Our goal is to raise healthy, happy puppies to the breed standard for families to love and enjoy as pets or for show homes.

DW

Raised by Deb W.

Lakeside Mastiffs of Minnesota · Meet breeder for pickup

We offer top quality Mastiffs that are well balanced and excel whether it be in the show ring or as a family companion.

Raised by Talia G.

Rosehill Mastiffs & Bulldogs · Drop-off to you

We offer AKC registered show quality & pet Mastiffs and Bulldogs from health tested, championed parents!

Raised by Cindy R.

Halfway Creek Farms · Drop-off to you

I raise Mastiffs with health, care, and temperament in mind, and am part of Good Dog's vetted network.

Raised by Lucy S.

ScottsCreek Mastiffs · Meet breeder for pickup

We work hard to produce healthy, well-rounded Mastiff puppies that will make others as happy as our dogs have made us!

Raised by Andrea M.

ACM Mastiffs · Drop-off to you

Please contact me directly at https://www.facebook.com/ACMMastiffs

MB

Raised by Mollie B.

Clearbrook Mastiffs · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Cricket P.

POEM's Haven · Drop-off to you

We responsibly breed, raise, & socialize healthy pups so others can enjoy the gift of living life with a dog!

Raised by Amy L.

Southern Star English Mastiffs · Meet breeder for pickup

We offer top-quality pets with a focus on health, happiness, and temperament. We hope you love our dogs as much as we do!

Raised by Jennifer G.

Jennifer s Appalachian Mountain Mastiffs · Drop-off to you

We understand the responsibility of purposefully breeding in order to do better for the breed and the families that love them!

Raised by Christi K.

Stone Gate Mastiffs · Meet breeder for pickup

We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.

KS

Raised by Kailey S.

Legacy Mastiffs · Drop-off to you

Our dogs are bred to have top qualities that all families want in their puppies, such as compassion, patience, and love!