40+ Mastiff puppies for sale from ethical breeders near Tupelo, MS
Tucker, dad
Vegas, mom
Raised by Julie A.
Beaver Creek Mastiffs · 60 miles away from Tupelo, MS
Our Mastiffs are raised with lots of love and pride. Making sure we provide you with the absolute best Mastiff puppy available.
Dolly, mom
Raised by JOSEPH T.
Trindade Mastiffs · 83 miles away from Tupelo, MS
We are a small family breeder focused on bettering the mastiff breed.
Page, mom
Page, mom
Raised by Cathy I.
Cedarhills · 125 miles away from Tupelo, MS
We offer top quality pups to loving homes
1 owner review
- LF
Raised by LaDonna F.
North Mississippi Mastiffs · 137 miles away from Tupelo, MS
We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!
We’ve screened nearly every breeder in the U.S.—only 1 in 5 meet our standard for responsible breeding.
Raised by Celeste G.
Liberty Mountain · 149 miles away from Tupelo, MS
We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.
Roxie, mom
Apollo, dad
Raised by Maria B.
Stoneheart Mastiffs · 155 miles away from Tupelo, MS
We do health testing and keep our dogs in tip top shape. They get expert vet care, great nutrition, and lots of love.
2 owner reviews
Juno, mom
Raised by Carolyn W.
Nytewind Mastiffs · 181 miles away from Tupelo, MS
I breed Mastiffs to improve the quality of the breed and to offer service dogs to people like myself. I love my dogs & what I do!
Knuckles, mom
Bjorn, mom
Raised by Lacy S.
Storytime Mastiffs & Bulldogs · 197 miles away from Tupelo, MS
At Storytime Mastiffs & Bulldogs we pride ourselves on breeding healthy puppies while also focusing on type and temperament.
Raised by Diane G.
Sylvan Mastiffs · 205 miles away from Tupelo, MS
Being a breeder is my passion, not my job. I love having the opportunity to share these wonderful companions with other families!
Samson, dad
Raised by David H.
Hillside Mastiffs · 209 miles away from Tupelo, MS
We breed high-quality mastiff/Great Dane puppies. We love what we do and are committed to producing well-bred, healthy puppies.
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Raised by Caleb W.
Ozark Mountain Mastiffs · 220 miles away from Tupelo, MS
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
Esther, mom
Dakota or Kota, dad
Raised by Suzie F.
Celtic's Mastiffs · 242 miles away from Tupelo, MS
I've had the honor to be owned by Mastiffs I've bred for many, many years. I can't imagine my life without them by my side.
Tyson, dad
Alisha, mom
GSRaised by Gary G. S.
Gary Schneider’s Mastiffs · Meet breeder for pickup
Our dogs and pups are raised in our home and are loved as family. We strive to produce high-quality show prospects and companions.
Raised by Alison R.
AKA Shih Tzu · Meet breeder for pickup
My program is built upon a foundation of love, admiration, and respect for the Shih Tzu and Mastiff breeds.
Male, reserved
Male, reserved
Raised by Karen W.
Lakeside English Mastiffs of Georgia and North Carolina · Drop-off to you
Our high-quality puppies are the result of extensive research and thorough care for our outstanding dogs and puppies.
1 owner review
Male, reserved
Female, reserved
Raised by Tim S.
Ozark Mountain Mastiffs · Drop-off to you
We are a small scale breeder who focuses on Mastiffs only.
25 owner reviews
Susie, mom
Kato, dad
Raised by Kristi L.
Kentucky Mastiffs · Meet breeder for pickup
I offer top-quality Mastiff puppies for families who share the same love and passion that I do for these lovely companions.
Female, available
Female, available
Raised by Karin C.
Hug-A-Mug Mastiffs · Meet breeder for pickup
I'm a preservationist breeder and passionate about the English Mastiff. I've been showing and breeding healthy litters since 1978.
Boogieman, dad
Zena, mom
Raised by Brian J.
MLJ Mastiffs Florida · Drop-off to you
We breed to enhance the breed with quality bone structure for size and genetics for health. We take great pride in our work!
Minni, mom
Raised by Michele & Andy P.
Parbury Place Mastiffs · Drop-off to you
We love the mellow temperament of these gentle giants and are excited to help other families find the perfect pup for their home.
Male, reserved
Female, reserved
Raised by Elizabeth R.
Riggins Mastiffs and Danes · Drop-off to you
We’re devoted to ensuring there are healthy Mastiffs for others to enjoy by responsibly growing this incredible breed.
Raised by Angela C.
Sovereign Mastiffs · Meet breeder for pickup
We responsibly breed, raise, & socialize healthy pups so others can enjoy the gift of living life with a Mastiff!
Willow, mom
Sara, mom
Raised by Candy P.
Southern Oaks Kennel · Meet breeder for pickup
Our goal is to raise healthy, happy puppies to the breed standard for families to love and enjoy as pets or for show homes.
1 owner review
Female, reserved
Male, reserved
Raised by Elesha P.
Mama’s Mastiffs · Meet 197 miles away from Tupelo, MS
Specializing in quality, DNA health tested, OFA certified English Mastiffs since 2006
4 owner reviews
Raised by Karen L.
Looking Glass English Mastiffs · Meet breeder for pickup
We absolutely love Mastiffs, and we aim to produce healthy and exceptional puppies that will thrive in their future homes.
Grantham, dad
Raven, mom
GSRaised by Gary S.
Two Ponds Mastiffs · Meet breeder for pickup
We here at Two Ponds Mastiffs have been raising and loving mastiffs for nearly 30 years.
Kaia, mom
Raised by Madison O.
M&M Aussie's & Mastiff's · Meet breeder for pickup
Faceb page with more information! M&M Aussies Of Monroe City ( trying to change the name since moved and added mastiffs)
Male, reserved
Male, reserved
Raised by Katie B.
Sunrise Mastiffs · Meet 250 miles away from Tupelo, MS
We’re a small, family oriented breeding program that focuses on exceptional temperament & health.
Raised by Jennifer T.
Mastiffs of Middle Earth · Meet breeder for pickup
We provide quality, healthy Mastiff puppies for special families.
Zuko, dad
Zucci, mom
JCRaised by Jordan C.
Big Z English Mastiff · Meet breeder for pickup
As conscientious breeders, we are proud of the loving, smart, beautiful, and sound puppies we’re able to provide for others.
Male, reserved
Female, reserved
Raised by Emma S.
King’s Peak Kennels · Drop-off to you
I offer quality-bred puppies for Mastiff enthusiasts. I strive to improve the breed and focus on conformation in my program.
Buttercup, mom
Raised by Talia G.
Rosehill Mastiffs & Bulldogs · Drop-off to you
We offer AKC registered show quality & pet Mastiffs and Bulldogs from health tested, championed parents!
Darth, dad
Watcher, mom
ESRaised by Erin S.
Kasota Farm · Drop-off to you
Our dogs are bred for health, temperament, and ability. We strive to produce beautiful and versatile beloved companions.
Marley, dad
Nymeria, mom
SCRaised by Sarah C.
SMC Mastiffs / Muddy Boots Cocker Spaniels and Cockapoos · Meet breeder for pickup
We breed quality health tested dogs that have excellent temperaments. Our goal is to produce amazing family members!!
Male, reserved
Female, reserved
Raised by Danielle P.
Little Mountain Mastiffs · Meet 250 miles away from Tupelo, MS
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
1 owner review
King, mom
TPRaised by Theresa P.
Theresa's Mastiffs · Meet breeder for pickup
We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.
- DC
Raised by David C.
David's Mastiffs · Meet breeder for pickup
We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.
Female, available
PARaised by Paige A.
P Diamond Mastiffs · Drop-off to you
Having a dog in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!
Booker, mom
Raised by Shari S.
Bowtied Lickers · Drop-off to you
We focus on intentional breeding so that we can produce quality puppies that are excellent representations of the standard.
Kia, mom
Raised by Lori C.
J and L Farms Mastiff’s · Drop-off to you
We offer AKC Championship Bloodline English Mastiffs we focus on healthy well breed dogs with good temperaments.
Lily, mom
Tulip, mom
Raised by Sandy H.
Red River Mastiff · Drop-off to you
We have AKC registered, family raised, loving, sweet temperaments, healthy English Mastiffs.
Raised by Regina H.
Lone Star Legends Mastiffs · Drop-off to you
I offer top-quality Mastiff puppies for families who share the same love and passion that I do for these lovely companions.
Related breeds
Mastiff
Buyer’s Guide
Nationally, prices usually range from $2,500 to $3,500. While it may cost more up front, starting with a healthy puppy can help you avoid costly issues later. These ranges reflect the care behind responsible breeding and offer a reliable view of what ethical breeding really costs.
About the Mastiff
The Mastiff is an ancient breed that is well-mannered and fearless. With proper socialization, this massive breed is a noble and calm companion.
Moderate energy
Energy level
Easy coat care
Coat care
High shedding
Shedding
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Frequently asked questions
What is the average cost of Mastiff puppies in Tupelo, MS?
Prices may vary based on the breeder and individual puppy for sale in Tupelo, MS. On Good Dog, Mastiff puppies in Tupelo, MS range in price from $2,250 to $3,500. We recommend speaking directly with your breeder to get a better idea of their price range.
Do Mastiff puppies in Tupelo, MS shed?
Mastiff puppies in Tupelo, MS are a high shedding breed. However, it's possible that a dog's level of shedding may vary by individual puppy.
What is the average size range of Mastiff puppies in Tupelo, MS?
The expected weight range for male Mastiff puppies in Tupelo, MS is 160 to 230 pounds. The expected weight range for female Mastiff puppies in Tupelo, MS is 120 to 170 pounds. Because size and weight may vary based on individual dogs, your dog may be outside of that range.
What is the average lifespan for Mastiff puppies in Tupelo, MS?
The average lifespan for Mastiff puppies in Tupelo, MS is 6 to 10 years of age.
Can I adopt a Mastiff from a rescue or shelter?
On Good Dog, you can search for Mastiff puppies or dogs in rescues and shelters near Tupelo, MS. Adopting a Mastiff from a shelter or rescue in Tupelo, MS is generally less expensive than buying a puppy from a breeder with ethical practices. Across the United States, there are dedicated rescues that specialize in specific breeds and may even help transport a Mastiff dog to you in Tupelo, MS from another part of the country. Although it can be more cost-effective, adopting the exact breed you're looking for is typically more difficult than working with a responsible breeder. Learn more about adopting a dog from a shelter or rescue.
About Good Dog
About Good Dog
Good Dog is your trusted partner for finding Mastiff puppies for sale near Tupelo, MS. Our vetted network of responsible Mastiff breeders makes it easy to search listings, connect directly, and ask questions — all in one safe, protected place. Work directly with breeders you can trust and complete payments securely through Good Dog, so you can bring home your Mastiff puppy with confidence.