40+ Great Dane puppies for sale from ethical breeders near Des Moines, IA

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Raised by Sarah S.

Trumans Great Danes · Meet breeder for pickup

We do all we can to prepare each one of our puppies to thrive in their new homes.

Raised by Erin S.

WZ Kennels · Drop-off to you

I focus on health, temperament, structure, & longevity. I love to create positive, lasting, relationships with my puppy families.

Raised by Chari M.

RCM Great Danes · Meet 179 miles away from Des Moines, IA

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

Raised by Taylor R.

Double R Danes · Drop-off to you

At Double R Danes, we are dedicated to offering quality puppies with amazing temperament, conformation, and health above all!

Raised by Stacy L.

Phoenix's Legacy Great Danes · Meet breeder for pickup

We offer Loved, Nurtured, Puppy Cultured, Healthy AKC registed puppies.

Raised by Lila T.

Moonwater Danes · Drop-off to you

We love to responsibly raise and train our puppies so they have the tools to be well-rounded, beloved family members.

Raised by Tyler and Sydni B.

Garden Grove Great Danes · Drop-off to you

We strive to produce colorful danes with good structure, great health, and the best temperaments.

Raised by Tisha B.

Barkingham Palace Danes · Drop-off to you

We offer top-quality, loving Great Danes. Babies are born and raised in our home. Puppies are raised using the rule of 7.

Raised by Kim T.

Thomas Family Danes · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

Raised by Emily P.

Phantasm Farms · Meet breeder for pickup

We are a small, intentional Great Dane breeder devoted to preserving the breed’s gentle nature, health, and structure.

Raised by DAYSHA B.

Breken Great Danes · Drop-off to you

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

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Raised by Tamela C.

Twin Oaks Danes · Meet breeder for pickup

Having a pup in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

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Raised by Pamela B.

Big Paw Great Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

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Raised by Kayla B.

Kayla's Great Danes · Meet breeder for pickup

Our puppies are excellent representations of their breed, and we are proud to offer our high-quality puppies to loving homes.

Raised by Sabrina V.

Victory Danes · Drop-off to you

Our high-quality Great Danes are the result of extensive research and thorough care for our outstanding dogs and puppies.

Raised by Janet T.

Taylor's Tails of Joy · Meet breeder for pickup

My focus is on maintaining the Great Dane standard by raising structurally sound and correct puppies with excellent temperaments.

Raised by Kelly M.

Dusty Dream Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

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Raised by Heather C.

Heather's Noble Saints · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Jason S.

Alpine Great Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Andrea A.

Apollo's Great Danes (AGD's) · Drop-off to you

We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.

Raised by Lori H.

Waterfront Danes · Meet breeder for pickup

I offer top-quality Great Dane puppies for families who share the same love and passion that I do for these lovely companions.

Raised by Sarah G.

Beaver Creek Danes · Drop-off to you

Located in the "mitten state" of Michigan, we focus on breeding Great Danes for health, temperament and longevity.

Raised by Abby E.

Mara Danes · Drop-off to you

Health tested parents OFA and Embark. LIFETIME genetic health and return contract

Raised by Christina C.

Northwood Euro Danes and Bassets · Drop-off to you

We are a small-scale breeding program with unique Great Danes. Our dogs are beautiful, healthy, well-tempered, and loved!

Raised by Jordan S.

River Valley Great Danes & Miniature Schnauzers · Drop-off to you

Our mission is to raise healthy, happy, adorable puppies and connect loving families with their new best friend!

Raised by Molly G.

Diamond Danes · Meet breeder for pickup

We believe the happiest of homes are those with a giant, cuddly, goofy Dane!

Raised by Pamela M.

Mielnickis Danes · Meet breeder for pickup

We raise our dogs with love in our home. We have high expectations for our pups and strive to pair each one with a loving family.

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Raised by Marie C.

Marie Chambers · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

Raised by Laura H.

Boxers and Great Danes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Elizabeth Y.

KISS Great Danes · Drop-off to you

We understand the importance of solid foundations and health test our lines to ensure we are breeding to the standards you expect.

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Raised by shari s.

Shari Skory's Great Danes & Old English Sheepdogs · Meet breeder for pickup

We breed to both help ensure the future of our breeds and to improve upon our dogs' fantastic traits with each generation.

Raised by Heather G.

Dream K9 · Drop-off to you

Having a dog in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

Raised by Kim G.

Garrow Danes House of Blues · Drop-off to you

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

Raised by Terrie R.

Terrie Rhoden Kirkland · Meet breeder for pickup

As a responsible breeder of Great Danes, I meet Good Dog's standards for health, care, and ethical practices.

Raised by Dusti B.

Tioli Great Danes · Drop-off to you

Striving for healthy and happy fawn and brindle Great Danes for companion and show homes.

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Raised by Tamara C.

Blue Diamond Danes · Drop-off to you

We have been raising Great Danes since 1995 and we We have loved and owned Boston Terriers for just over 16 years.

Raised by Robin P.

Aidens Great Danes · Drop-off to you

Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.

Raised by Cherie L.

Bellator Danes & Mini Dachshunds · Meet breeder for pickup

We breed quality AKC Mini Dachshunds & Great Danes. They are not just pets but our family members.

Raised by Keri W.

Southern Grace Great Danes · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friends!

Raised by Jodi L.

Borealis Danes · Meet breeder for pickup

I offer well-tempered, health-tested Great Danes for loving homes. They are happy, intelligent, and cute as can be!

Raised by Peggy C.

Nikolodeon Danes · Drop-off to you

We offer top quality, loving family pets with a focus on health and temperament.

Raised by Kelsey F.

K.C. Kennels · Drop-off to you

We take great pride in breeding to produce pups that are the total package.