40+ Great Dane puppies for sale from ethical breeders near Myrtle Beach, SC

Raised by Lisa F.

Above The Salt Danes · Meet breeder for pickup

We offer exceptional quality puppies for a variety of homes including pet, breeding, and service homes. Our dogs are our pride!

Raised by Ed E.

Rocky Road Chocolate Danes · Drop-off to you

We raise adorable, affectionate, versatile puppies, and give them the best possible start for a life of companionship and love!

Raised by Connie H.

Timeless Danes · Drop-off to you

We are experienced breeders of top-quality Great Danes. Our puppies are raised with care, and we only sell to responsible homes.

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Raised by Stacy L.

Pink Star Danes and French Bulldogs · Drop-off to you

Many of our puppies have become exceptional show dogs, and all of them have become excellent family dogs and lifelong friends.

Raised by Joyel C.

Joyel's Great Danes · Meet breeder for pickup

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by Samantha D.

The Great French ( Great Danes + Frenchies ) · Meet breeder for pickup

We focus on health, temperament & structure! All of our breeding dogs are raised in home, health tested, & have obedience titles.

Raised by Ashley L.

Swanger Danes · Drop-off to you

We raise our dogs with love in our home. We have high expectations for our pups and strive to pair each one with a loving family.

Raised by Callie D.

Unity Great Danes & Staffs · Meet breeder for pickup

Hobby breeders who show and health test our dogs. Teaching puppies to be family companions and great social breed ambassadors.

Raised by Carolyn B.

MommaDukes Danes · Drop-off to you

Breeding beautiful, healthy, structurly sound, smart puppies. Raised with love in our home for other families to love!

Raised by Jackie v.

VanDelft Danes · Meet breeder for pickup

Established 2012; AKC Breeder Of Merit. Black & Fawn Great Danes.

Raised by Natalie L.

RP DANES · Meet 62 miles away from Myrtle Beach, SC

Pups will come with -AKC papers -Vaccines -microchip -dewormed

Raised by Michelle P.

Babydoll Bullies & Danes · Meet breeder for pickup

Our Great Danes come from European Champion bloodlines. We OFA test our dams & sires

Raised by Nicole K.

Kirk’s Dane Farm · Meet breeder for pickup

We strive to produce temperamentally sound and healthy puppies with each breeding.

Raised by Keri W.

Southern Grace Great Danes · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friends!

Raised by Jessica B.

Bauman Great Danes · Drop-off to you

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Jayden M.

R&R Breeding and Pet Care · Drop-off to you

We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.

Raised by Judy A.

Danny's Danes · Meet breeder for pickup

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

Raised by Kelly M.

Dusty Dream Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Jade I.

Gentle Giant Companions · Drop-off to you

We offer top quality Great Danes as pets, with a focus on health and temperament.

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Raised by Heather C.

Heather's Noble Saints · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Emily P.

Phantasm Farms · Meet breeder for pickup

We are a small, intentional Great Dane breeder devoted to preserving the breed’s gentle nature, health, and structure.

Raised by Michael U.

F&B Kennels · Drop-off to you

Breeding Great Danes based on health, temperament, and longevity. Traditional and alternative colors, with traditional structure.

Raised by Morgan S.

LakeSide Danes · Drop-off to you

We offer top quality, loving and loyal family pets, focusing on temperament.

Raised by Prophecy D.

Prophecy Danes · Drop-off to you

We are lovers and breeders of quality purebred AKC Great Danes. We breed for health, temperament & longevity. They are our life!

Raised by Bluestone V.

Bluestone Valley Great Danes · Meet 154 miles away from Myrtle Beach, SC

Our dogs are bred for health, temperament, and conformation. We strive to produce quality pets that are true to breed standards.

Raised by Rebeka B.

Alchemy Danes · Meet breeder for pickup

We at Alchemy Danes strive for the health and longevity of the Great Dane Breed. Our dogs and puppies are our pride and joy!

Raised by DAYSHA B.

Breken Great Danes · Drop-off to you

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

Raised by Michelle M.

De Leon Danes · Drop-off to you

My goal is to increase the longevity of Great Danes. My dogs are not bred for their color or height; they're bred for health.

Raised by Jason S.

Alpine Great Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Joanna M.

Catskills Greatest Danes · Meet breeder for pickup

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

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Raised by Tamela C.

Twin Oaks Danes · Meet breeder for pickup

Having a pup in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

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Raised by Pamela B.

Big Paw Great Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

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Raised by Kayla B.

Kayla's Great Danes · Meet breeder for pickup

Our puppies are excellent representations of their breed, and we are proud to offer our high-quality puppies to loving homes.

Raised by Machelle M.

M&J Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

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Raised by Pamela H.

House of Henry Great Danes 2 · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

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Raised by Destiny m.

Moonstone Danes · Meet breeder for pickup

All of our dogs are loved as family members. We cherish our puppies from birth up until they leave our arms to snuggle into yours!

Raised by Heather W.

Genai Great Danes · Meet breeder for pickup

Our name, Genai, means "the one whom everyone loves." We love our Danes, and we hope you will too’

Raised by Emily H.

North Park Great Danes · Drop-off to you

We are a preservation breeding program that only has a litter every few years.We breed for health, temperament, and conformation.

Raised by

Rockin' Danes · Drop-off to you

AKC Champions/OFA tested parents! Our dogs are bred for health, temperament, and train-ability. Show And Excellent pet/companions.

Raised by John & Mandy W.

Weslow AKC Danes · Drop-off to you

We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.

Raised by Amanda R.

Southern Beauty Danes · Meet breeder for pickup

We're new breeders starting a small program. We hope to help provide families with quality puppies as we continue to learn & grow!

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Raised by Sherry D.

Sherwood Mastiffs · Drop-off to you

We offer high-quality puppies. Our dogs are excellent representations of their breeds, and we are proud to continue their lines.