40+ Great Dane puppies for sale from ethical breeders near South Carolina
Raised by Karmen U.
Underwood Danes AKC · Meet breeder for pickup
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
- CM
Raised by Christy M.
QC MOSS DANES · Meet breeder for pickup
Having a dog in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!
- Kl
Raised by Kathy l.
Kwdanes · Meet breeder for pickup
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
- TM
Raised by Tiffany M.
Infinity Danes · Meet breeder for pickup
We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.
We’ve screened nearly every breeder in the U.S.—only 1 in 5 meet our standard for responsible breeding.
Scooby, dad
Velma, mom
THRaised by Tracey H.
Bonetown Great Danes · Drop-off to you
We love to responsibly raise and train our puppies so they have the tools to be well-rounded, beloved family members.
Toot, mom
Cino, dad
Raised by Brittany J.
Massive Creations · Drop-off to you
Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friend!
Baby, mom
Spotticus, mom
Raised by Bonnie B.
Windy Knoll Great Danes · Meet breeder for pickup
Please check with your housemates, spouse, partner or parents PRIOR to messaging. Payoff is due 1 week before pup goes home.
4 owner reviews
Female, reserved
Male, reserved
MMRaised by Meghan M.
Gentry Farm Danes · 55 miles away from South Carolina
I breed Great Danes responsibly, prioritizing health, temperament, and lifelong success for each dog.
- KP
Raised by Karen P.
A20 Danes · 65 miles away from South Carolina
Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.
Vaeda, mom
Cowboy, dad
Raised by elizabeth l.
DoodleDandy & Danes · Meet-up offered 98 miles away from South Carolina
Having a dog in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!
2 owner reviews
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Zuber, mom
Raised by Marisa
Double Doo Ranch · Meet breeder for pickup
We love these pups! We love Great Danes, in general. Smart, loyal and loving, we know you’ll love them too!
Raised by Sue B.
Sanctuary Great Danes · Drop-off to you
We offer top quality, loving family pets and show dogs with a focus on health and temperament.
Male, available
Female, available
Raised by Caitlin L.
Pawlmetto Danes · Meet 89 miles away in Spartanburg, SC
We strive to pair the best Danes, to keep our bloodline pristine and in good health!
Male, reserved
Male, reserved
Raised by Maria M.
Divine Blue Angels Great Danes · Drop-off to you
Our mission is to bring amazing healthy Great Danes into the world to provide love and support.
Female, available
Female, available
Raised by Susan A.
Allen’s Ridge Ranch · Meet 109 miles away in Landrum, SC
We offer top-quality pups from carefully planned litters. We focus on temperament, soundness,health, conformation, and longevity
- TH
Raised by Terri H.
Triple D Danes · 112 miles away from South Carolina
Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friend!
Carolina, mom
Patriot, dad
Raised by Chris B.
Blackmon Family Danes · Drop-off to you
Having a Great Dane is not like having a pet, it is a whole way of life that we love very much! Our dogs are our pride and joy!
- LM
Raised by Lori M.
LoriDanes Great Danes · 114 miles away from South Carolina
I have had Great Danes for 25 years: have been involved in the AKC show world for about 10 years. 100% BRED to GDCA standards.
Lylah, mom
Honey, mom
Raised by Kristy V.
Carolina Great Danes & Toy Poodles · 119 miles away from South Carolina
Carolina Great Danes & Toy Poodles raises healthy, well-socialized puppies that bring years of joy to their forever families.
24 owner reviews
Raised by Treasure W.
Treasure Wylie · 126 miles away from South Carolina
I produce pups that will continue to excel in their chosen field, whether that be working, showing, or as an active companion.
Female, reserved
Male, reserved
Raised by Sarah A.
Outback Danes · Drop-off to you
Raising Quality, AKC Registered Great Danes from Health Tested Parents with a Splash of Color.
Female, available
Raised by Jennifer D.
Days Danes · Meet breeder for pickup
We offer top quality, family pets with a focus on health and temperament.
Male, available
Female, available
TCRaised by Tammy C.
Clouser's Bodacious Danes & Miniature Schnauzers · 132 miles away from South Carolina
We are proud to offer our Great Dane & Mini Schnauzer puppies to loving homes! Our dogs are healthy & have great temperaments.
3 owner reviews
Raised by Crystal B.
CAB Danes · 145 miles away from South Carolina
I am a proud breeder of Great Danes focusing on quality, health, show, and companionship. I love my dogs and what I do.
Delilah, mom
LRRaised by Linnea R.
Duke and Duchess Danes · 153 miles away from South Carolina
We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!
Chronus, dad
June, mom
AERaised by Adam E.
Titans Legacy Danes · 153 miles away from South Carolina
All of our dogs are loved as family members. We cherish our puppies from birth up until they leave our arms to snuggle into yours!
- BW
Raised by BJ W.
BJ's Great Danes · 153 miles away from South Carolina
We breed high-quality Great Danes. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.
Tyga, dad
Honey, mom
Raised by Ryley N.
Rivercliff Danes · 156 miles away from South Carolina
We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.
Storm, mom
Raised by Stephanie C.
Tidal Wave Danes · 157 miles away from South Carolina
We are devoted to raising Health Tested, quality AKC Great Danes.
- BM
Raised by Brenda M.
Majestic Danes · 160 miles away from South Carolina
Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.
Glitter, mom
Raised by Jennifer F.
Dynamic Danes · 171 miles away from South Carolina
All of our Danes are raised indoors and are pets first. My Danes are completely health tested and stay with me after retirement.
Raised by Lorraine R.
VZTop Danes · 173 miles away from South Carolina
My focus is on maintaining the Dane breed standard by raising structurally sound & correct puppies with excellent temperaments.
Raised by Jennifer N.
Newton's AKC Great Dane's · 180 miles away from South Carolina
We raise our dogs with love in our home. We have high expectations for our pups and strive to put each one into a loving family.
Raised by Audrey B.
Azal Great Danes · 180 miles away from South Carolina
The Great Dane breed is an exceptional breed that we love and cherish.
Raised by Heather S.
DSD Danes · 180 miles away from South Carolina
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
Raised by Lisa H.
Selah Great Danes & Chinese Cresteds · 180 miles away from South Carolina
The health of our dogs always comes first. We're committed to ethical breeding & a continued effort to enhance the breed standard.
Bruna, mom
Monte, dad
Raised by shannon J.
Tarheel danes · 180 miles away from South Carolina
We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.
- AA
Raised by Alyssa A.
TLC B & G KENNELZ · 180 miles away from South Carolina
We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.
Raised by Darryl P.
Stardust Danes · 183 miles away from South Carolina
I have been breeding top-quality Great Danes since 2013. I focus on health, pedigree, and beauty. I love my dogs and what I do!
Rheya, mom
Willow, mom
KKRaised by Kaitlynn K.
Black Tie Danes · 192 miles away from South Carolina
Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.
Female, reserved
Raised by Lori R.
Gentle Giant Danes, LLC · 193 miles away from South Carolina
We decided to start breeding to share the best possible puppies with excellent personalities, temperament, and most of all health!
Raised by Misty M.
Misty Creek · 194 miles away from South Carolina
We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.
Related breeds
Great Dane
Buyer’s Guide
Nationally, prices usually range from $2,000 to $3,000. While it may cost more up front, starting with a healthy puppy can help you avoid costly issues later. These ranges reflect the care behind responsible breeding and offer a reliable view of what ethical breeding really costs.
About the Great Dane
This dog is magnificent, combining great size and commanding appearance with a surprising amount of gentleness and, yes, goofiness. Learn more
Moderate Energy
Energy level
Minimal Maintenance
Grooming
Average Trainability
Trainability
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About Good Dog
About Good Dog
Good Dog is your trusted partner for finding Great Dane puppies for sale near you. Our vetted network of responsible Great Dane breeders makes it easy to search listings, connect directly, and ask questions — all in one safe, protected place. Work directly with breeders you can trust and complete payments securely through Good Dog, so you can bring home your Great Dane puppy with confidence.