40+ Great Dane puppies for sale from ethical breeders near South Carolina

Raised by Ed E.

Rocky Road Chocolate Danes · Drop-off to you

We raise adorable, affectionate, versatile puppies, and give them the best possible start for a life of companionship and love!

Raised by Samantha F.

Ferguson Family Danes LLC · Drop-off to you

Welcome to Ferguson Family Danes where we connect Great Puppies with Great Families! We are a small in-home family run business.

TC

Raised by Tamela C.

Twin Oaks Danes · Meet breeder for pickup

Having a pup in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

PB

Raised by Pamela B.

Big Paw Great Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Leslie W.

Leslie Woodard's Great Danes · Drop-off to you

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by Jason S.

Alpine Great Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Connie H.

Timeless Danes · Drop-off to you

We have been showing and breeding Great Danes for over 20 years.

Raised by Callie D.

Unity Great Danes & Staffs · Meet breeder for pickup

Hobby breeders who show and health test our dogs. Teaching puppies to be family companions and great social breed ambassadors.

Raised by Jackie v.

VanDelft Danes · Meet breeder for pickup

Established 2012; AKC Breeder Of Merit. Black & Fawn Great Danes.

SR

Raised by Stephanie R.

Reagan’s Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Lisa F.

Above The Salt Danes · Drop-off to you

We offer exceptional quality puppies for a variety of homes including pet, breeding, and service homes. Our dogs are our pride!

Raised by Morgan S.

LakeSide Danes · Drop-off to you

We offer top quality, loving and loyal family pets, focusing on temperament.

Raised by Erika S.

BkB’s House of Danes · Meet breeder for pickup

Our mission is to raise healthy, happy, beautiful Great Dane puppies and connect loving families with their new best friends!

BG

Raised by Betsy G.

Dream Danes · Meet breeder for pickup

We breed high-quality Great Danes. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Steffi Sabrina S.

White Pine Acres K9 · Meet breeder for pickup

Our AKC Great Dane puppies are born, raised,& cared for inside our home in NJ. Breeding for health, temperament, and confirmation!

Raised by Brian F.

East Coast Great Danes · Meet breeder for pickup

We raise our puppies with total care and attention so they can become well-socialized and loving additions to their forever homes.

Raised by Vicki M.

Vicki's Danes and frenchies · Meet breeder for pickup

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by Paula L.

Paula Lloyd's Great Danes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

RV

Raised by Raeleen V.

Vazquez Family Danes · Meet breeder for pickup

We love to responsibly raise and train Great Danes so they have the tools to be well-rounded, beloved family members.

Raised by Cortney R.

Cortney's Great Danes · Meet breeder for pickup

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

KW

Raised by Kait W.

Kait's Danes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Trisha L.

TriLa Great Danes · Meet breeder for pickup

We offer high-quality Great Dane puppies to show and companion homes. We breed for health, temperament, and conformation.

KJ

Raised by Kathy J.

Kathy's Pups · Meet breeder for pickup

We care deeply about our dogs and have built that love and respect for the breed into every aspect of our program.

Raised by Taylor R.

Double R Danes · Drop-off to you

At Double R Danes, we are dedicated to offering quality puppies with amazing temperament, conformation, and health above all!

Raised by Machelle M.

M&J Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

Raised by Dee G.

Gresko Danes · Meet breeder for pickup

AKC registered. I breed for the breed and to improve the breed. My dogs are color correct through over 6 generations.

Raised by Dustin & Karen M.

7Sisters Great Danes · Drop-off to you

We value responsible breeding practices and want to do our part to ensure the Great Dane breed will continue to thrive.

Raised by Lori H.

Waterfront Danes · Meet breeder for pickup

I offer top-quality Great Dane puppies for families who share the same love and passion that I do for these lovely companions.

Raised by John & Mandy W.

Weslow AKC Danes · Drop-off to you

We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.

Raised by Amanda R.

Southern Beauty Danes · Meet breeder for pickup

We're new breeders starting a small program. We hope to help provide families with quality puppies as we continue to learn & grow!

Raised by Judy A.

Danny's Danes · Meet breeder for pickup

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

Raised by Erin S.

WZ Kennels · Drop-off to you

I focus on health, temperament, structure, & longevity. I love to create positive, lasting, relationships with my puppy families.

SD

Raised by Sherry D.

Sherwood Mastiffs · Drop-off to you

We offer high-quality puppies. Our dogs are excellent representations of their breeds, and we are proud to continue their lines.

Raised by Dana M.

Vail Great Dane · Meet breeder for pickup

We are a passionate and dedicated breeding program that produces dogs with great obedience, conformation, and agility.

Raised by Michael U.

F&B Kennels · Drop-off to you

Danes and Shepherds based on health, temperament, and longevity. Traditional and alternative colors, with traditional structure.

Raised by Sharon H.

Hladik Great Danes · Drop-off to you

We breed and show top-quality dogs. Our heavy involvement in the show world speaks to the standards that we breed our dogs by.

Raised by Laurie S.

Poke-A-Nose Danes · Drop-off to you

I love being a breeder. My focus is on raising structurally correct Great Dane puppies with excellent health and temperaments.

Raised by Lisa H.

Pocono Mountain Great Danes · Meet breeder for pickup

We love to responsibly raise and train our puppies so they have the tools to be well-rounded, beloved family members.

Raised by Kennedy M.

Giants and Munchkins · Drop-off to you

We focus on intentional breeding so that we can produce quality puppies that are excellent representations of the standard.

Raised by Prophecy D.

Prophecy Danes · Drop-off to you

We are lovers and breeders of quality purebred AKC Great Danes. We breed for health, temperament & longevity. They are our life!

Raised by Glenda T.

T3 Enchanted Forrest Danes · Drop-off to you

We are a small scale family owned/operated European Great Dane Breeder.

Raised by Kaitlyn K.

Lazuli Great Danes & Bare Necessities American Hairless Terriers · Drop-off to you

We offer AKC registered Great Danes and American Hairless Terriers focusing on health, temperament, conformation, and longevity.