40+ Great Dane puppies for sale from ethical breeders near South Carolina

Raised by Sarka V.

Ajani's Danes · Drop-off to you

We love this breed and do everything we can to help it thrive. We give each of our dogs and puppies the best care that we can.

Raised by Jill G.

Windy Ridge Danes · Drop-off to you

We offer well-rounded puppies who will excel in any adventure with their new family.

Raised by Shannon C.

Sand Dollar Danes · Meet breeder for pickup

We strive to better the breed and breed for health, temperament and confirmation.

Raised by Amber F.

EverAfter Danes · Meet breeder for pickup

We enjoy showing our dogs and occasionally offer puppies from our high-quality Great Danes. We are proud of our dogs and pups.

Raised by Meredith M.

Long Hall Danes · Drop-off to you

We breed high-quality Danes. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

GB

Raised by Gloria B.

Sylcrest · Meet breeder for pickup

We breed and show our dogs out of a love for and dedication to the protection and betterment of the breed.

KA

Raised by Kathy A.

AnayaDanes · Meet breeder for pickup

We're committed to raising well-rounded Great Dane puppies who can excel in any venue with their new families.

RN

Raised by Rhonda N.

Danes of Distinction · Meet breeder for pickup

Our pups are home-raised. We put a lot of care into socializing them so they can transition easily into their new lives.

DS

Raised by Dawn S.

BLK's Great Danes · Meet breeder for pickup

We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.

Raised by Cyndi C.

King of Clubs · Drop-off to you

Many of our puppies have become exceptional show dogs, and all of them have become excellent family dogs and lifelong friends.

MC

Raised by Morgan C.

Low Acres Homemaker · Meet breeder for pickup

We love to responsibly raise and train our puppies so they have the tools to be well-rounded, beloved family members.

Raised by LeeAnne F.

Lotsaspots Danes · Drop-off to you

We offer top quality Great Danes from health tested parents, for pet and show.

Raised by Elizabeth S.

Iron Horse Kennel · Meet breeder for pickup

We pride ourselves on providing quality puppies with good health, conformation and temperament.

Raised by Valerie D.

Von Schaaf Haus DuPree · Meet-up offered 98 miles away from South Carolina

Top breeding practices & OFA testing for our European Doberman Pinschers & Great Danes. Sound structure and excellent temperament.

Raised by Michelle P.

Babydoll Bullies & Danes · Meet breeder for pickup

Our Great Danes come from European Champion bloodlines. We OFA test our dams & sires

MZ

Raised by Mary Anne Z.

Giant Step Great Danes · Meet breeder for pickup

We hold ourselves to the highest standard when it comes to our dogs and our policies. We take responsible breeding very seriously.

Raised by Jenna G.

Myshire Danes · Meet breeder for pickup

We decided to start breeding to share the best possible puppies with excellent personalities, temperament, and most of all health!

MB

Raised by Michael B.

Dandelion Farm Dogs · Meet breeder for pickup

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

LR

Raised by Lori R.

Jaylor Danes · Meet breeder for pickup

We care deeply about Great Danes and have built that love and respect for the breed into every aspect of our program.

Raised by Toni- Bagnato G.

MEJADANES · Meet breeder for pickup

Our Great Danes are excellent representations of their breed, and we are proud to offer our high-quality puppies to loving homes.

JB

Raised by Jennifer B.

Spiritual Danes · Meet breeder for pickup

We focus on intentional breeding so that we can produce quality puppies that are excellent representations of the standard.

Raised by Elizabeth M.

Danes By The Bay · Meet breeder for pickup

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Heather G.

City Slicker Danes · Drop-off to you

We raise our dogs and puppies in our home like they are family. We live and breathe for our Danes.

CB

Raised by Christina B.

Danes of Cherry Tree · Meet breeder for pickup

Offering four-legged family members for your home. All of our puppies are raised indoors to produce happy family companions!

BC

Raised by Beth C.

V Yukon · Drop-off to you

Our puppies are excellent representations of their breed, and we are proud to offer our high-quality puppies to loving homes.

Raised by Keri W.

Southern Grace Great Danes · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friends!

Raised by Maryann I.

HCC Great Danes · Drop-off to you

We have a small AKC breeding program. We breed for quality over quantity, healthy pups with great temperaments.

Raised by Kayla A.

Country Danes · Drop-off to you

We breed Great Danes for conformation, health, temperament, and longevity.

KL

Raised by Kelsey L.

Good Town Kennels · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friend!

Raised by Amanda D.

Chesapeake Blues Great Danes · Drop-off to you

We strive to breed the best champion European lines with high quality standards.

Raised by Sandee Y.

Sundara Danes · Drop-off to you

I’m an ambassador of the Great Dane. It is my goal to breed dogs with sound minds and bodies. I am very proud of my dogs!

NS

Raised by Nic S.

Nics Great Danes · Meet breeder for pickup

All of our puppies are bred, raised, and loved indoors to produce happy, healthy pets for those seeking the best family companion!

CS

Raised by Carolyn S.

SS Majesty Danes · Meet breeder for pickup

Our dogs are bred to have top qualities that all families want in their puppies, such as compassion, patience, and love!

Raised by Rhonda W.

Southern Ohio Great Danes · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friends!

DC

Raised by Debbie C.

Debbie's Pups · Meet breeder for pickup

Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.

MS

Raised by Madison S.

Madison’s Great Danes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

JT

Raised by Jen T.

Scoobz Crew Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Gregory G.

GrinerDanes · Meet breeder for pickup

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by Amanda Y.

Danes of Dundee · Drop-off to you

We are dedicated to producing happy and health Great Dane puppies for loving and caring homes.

Raised by Amber B.

E.C. Prophetic Danes · Drop-off to you

We are breeding the best pups with great temperaments for you to add to your home and love. Our dogs are family and we love them!

Raised by Dawn & Jon C.

Chapman House of Danes · Meet breeder for pickup

We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.

Raised by T. Lynn A.

MoonRiver Danes · Drop-off to you

We breed quality show dogs. We do everything we can to better the breed.