40+ Great Dane puppies for sale from ethical breeders near South Carolina

Raised by Greg G.

Griner Danes · Drop-off to you

We’re expecting fawn and brindle puppies mid-April 2024!

Raised by Katelyn S.

Starr Creek Danes & Frenchies · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Emily P.

Phantasm Farms · Meet breeder for pickup

We are a small, intentional Great Dane breeder devoted to preserving the breed’s gentle nature, health, and structure.

Raised by Amelia L.

Elja Danes · Drop-off to you

We love to responsibly raise and train Great Danes so they have the tools to be well-rounded, beloved family members.

Raised by DAYSHA B.

Breken Great Danes · Drop-off to you

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

Raised by Kim O.

K & J Danes · Drop-off to you

We offer quality Great Danes with health and temperament in mind! They are raised indoors as family members first. We love them!

Raised by Kelly M.

Dusty Dream Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

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Raised by Pamela H.

House of Henry Great Danes 2 · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

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Raised by Destiny m.

Moonstone Danes · Meet breeder for pickup

All of our dogs are loved as family members. We cherish our puppies from birth up until they leave our arms to snuggle into yours!

Raised by Jessica L.

Epic Prince Dutton · Meet breeder for pickup

I’m offering Dutton up as a stud for your female! He has the best temperament, great health lines, and registered with Akc.

Raised by Tiffany G.

Skye Blue Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

Raised by Heather W.

Genai Great Danes · Meet breeder for pickup

Our name, Genai, means "the one whom everyone loves." We love our Danes, and we hope you will too’

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Raised by Dana G.

Dana's Danes · Drop-off to you

Danas Danes has been breeding high quality Danes for 5 years. We have service dogs in our linage.

Raised by Jennifer H.

Ocean Blue Danes · Drop-off to you

Producing quality black and blue Great Danes following the breed standard set forth by the Great Dane Club of America.

Raised by Amanda F.

Guilty Pleasure Great Danes · Drop-off to you

We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.

Raised by Heather S.

Vegas Danes · Meet breeder for pickup

Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.

Raised by Wendy C.

Weco Danes · Meet breeder for pickup

Weco Danes is built upon a foundation of love, admiration, & respect for the Great Dane. We offer top-quality pups bred with love!

Raised by Amber G.

Urban Danes and bulldogs · Drop-off to you

Our Great Dane pups are home-raised. We put a lot of care into socializing them so they transition easily into their new lives.

Raised by Danica P.

MorningStarz Great Danes · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friends!

Raised by Lydia J.

Blue Mountain Great Danes LLC · Drop-off to you

Our Great Danes are the result of extensive research and thorough care for our dogs and puppies.

Raised by Juanita K.

Misty's Puppies · Meet breeder for pickup

We raise our dogs with love in our home. We have high expectations for our pups and strive to put each one into a loving family.

Raised by Kelsey F.

K.C. Kennels · Drop-off to you

We take great pride in breeding to produce pups that are the total package.

Raised by Laura O.

Kindred Spirit Danes · Meet breeder for pickup

We breed for temperment, health, longevity, conformation, and athleticism.

Raised by Cindy C.

Absolute Sasdania · Meet breeder for pickup

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

Raised by Nicole K.

Kirk’s Dane Farm · Meet breeder for pickup

We strive to produce temperamentally sound and healthy puppies with each breeding.

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Raised by Rhonda O.

Heartfelt Danes · Drop-off to you

All of our puppies are bred, raised, and loved indoors to produce happy, healthy pets for those seeking the best family companion!

Raised by Amber S.

Danes From The Crick · Meet breeder for pickup

I focus on raising Great Danes with strong health foundations, early socialization, and careful matching to new homes.

Raised by Clairessa S.

Beachside Kennels · Drop-off to you

We love to responsibly raise and train Great Danes so they have the tools to be well-rounded, beloved family members.

Raised by Jessica B.

Bauman Great Danes · Drop-off to you

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Michelle C.

Campbell Great Danes · Drop-off to you

Puppies are raised in our home. They come from AKC champion bloodlines. Parent dogs are OFA tested. Puppies are AKC registered.

Raised by Amber H.

Loyal-Loves Great Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Tina H.

Broken Arrow Danes · Drop-off to you

We are a small hobby breeder of Great Danes focusing on health, temperament, and conformation.

Raised by Ashley L.

Swanger Danes · Drop-off to you

We raise our dogs with love in our home. We have high expectations for our pups and strive to pair each one with a loving family.

Raised by Megan T.

Megan Toeller · Meet breeder for pickup

Located in Memphis, TN, KDT Danes is a small preservation breeder with typically only 1 litter per year.

Raised by Neil L.

Lentz Great Danes · Meet breeder for pickup

We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.

Raised by Ed E.

Rocky Road Chocolate Danes · Drop-off to you

We raise adorable, affectionate, versatile puppies, and give them the best possible start for a life of companionship and love!

Raised by Samantha F.

Ferguson Family Danes LLC · Drop-off to you

Welcome to Ferguson Family Danes where we connect Great Puppies with Great Families! We are a small in-home family run business.

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Raised by Tamela C.

Twin Oaks Danes · Meet breeder for pickup

Having a pup in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

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Raised by Pamela B.

Big Paw Great Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

KB

Raised by Kayla B.

Kayla's Great Danes · Meet breeder for pickup

Our puppies are excellent representations of their breed, and we are proud to offer our high-quality puppies to loving homes.

Raised by Leslie W.

Leslie Woodard's Great Danes · Drop-off to you

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by Jason S.

Alpine Great Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.