40+ Great Dane puppies for sale from ethical breeders near O'Fallon, MO

Raised by Megan T.

Wild Willow Danes · Meet breeder for pickup

We are a quality family Great Dane breeder prioritizing genetic health and friendly personalities.

TC

Raised by Tamara C.

Blue Diamond Danes · Drop-off to you

We have been raising Great Danes since 1995 and we We have loved and owned Boston Terriers for just over 16 years.

Raised by Maryann I.

HCC Great Danes · Drop-off to you

We have a small AKC breeding program. We breed for quality over quantity, healthy pups with great temperaments.

CF

Raised by Carson F.

Caeruleum Danes · Meet breeder for pickup

We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.

Raised by Tabitha M.

Pigeon Mtn. House of Danes · Meet breeder for pickup

We are breeders of high-quality, European, color pure Great Danes who love our dogs and are dedicated to providing excellence.

Raised by Hunter T.

Gemini Danes · Meet breeder for pickup

We hold ourselves to high standards for the integrity of our program. All of our puppies are socialized, nurtured, and loved!

Raised by Machelle M.

M&J Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

Raised by Kalina W.

Sovereignty Woods Great Danes · Drop-off to you

We are a small home based, family style breeding program of atypical color AKC Great Danes.

Raised by Kimberly L.

Harrison Danes · Drop-off to you

We offer quality, loving pets. Our desire is to breed for health, temperament and give puppies the best beginnings!

JR

Raised by Jose R.

Jerdans Great Danes · Meet breeder for pickup

We enjoy showing our dogs and occasionally offer puppies from our high-quality Great Danes. We are proud of our dogs and pups.

Raised by Laura L.

Starry Night Great Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

MB

Raised by Michael B.

Dandelion Farm Dogs · Meet breeder for pickup

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

LR

Raised by Lori R.

Jaylor Danes · Meet breeder for pickup

We care deeply about Great Danes and have built that love and respect for the breed into every aspect of our program.

Raised by Robin H.

Hagerman Danes · Meet breeder for pickup

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Rachel K.

Solomon Valley Great Danes. · Meet breeder for pickup

We understand the importance of solid foundations and health test our lines to ensure we are breeding to the standards you expect.

JS

Raised by Jess S.

Forget Me Not Danes · Meet breeder for pickup

We’re proud of the healthy, affectionate, and behaviorally well-rounded puppies we raise for other families to love!

Raised by Valerie D.

Von Schaaf Haus DuPree · Drop-off to you

Top breeding practices & OFA testing for our European Doberman Pinschers & Great Danes. Sound structure and excellent temperament.

Raised by Peggy C.

Nikolodeon Danes · Drop-off to you

We offer top quality, loving family pets with a focus on health and temperament.

Raised by Callie T.

OnPoint Great Danes · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Fay R.

Sumner Great Danes · Meet breeder for pickup

At Sumner Great Danes, we love and cherish our beloved Great Danes and strive to produce sound bodies and sound minds.

Raised by Sarah L.

Wheaton Prairie Danes-www.wpdanes.com · Drop-off to you

We are a small breeder of AKC Great Danes with a focus on healthy, happy, and sound temperaments. www.wpdanes.com

KG

Raised by Kitty G.

KKDanes · Drop-off to you

We understand the responsibility of purposefully breeding in order to do better for the breed and the families that love them!

Raised by Andrea H.

Not So Dainty Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Chari M.

RCM Great Danes · Meet 209 miles away from O'Fallon, MO

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

MZ

Raised by Mary Anne Z.

Giant Step Great Danes · Meet breeder for pickup

We hold ourselves to the highest standard when it comes to our dogs and our policies. We take responsible breeding very seriously.

Raised by Sandee Y.

Sundara Danes · Drop-off to you

I’m an ambassador of the Great Dane. It is my goal to breed dogs with sound minds and bodies. I am very proud of my dogs!

NS

Raised by Nic S.

Nics Great Danes · Meet breeder for pickup

All of our puppies are bred, raised, and loved indoors to produce happy, healthy pets for those seeking the best family companion!

CS

Raised by Carolyn S.

SS Majesty Danes · Meet breeder for pickup

Our dogs are bred to have top qualities that all families want in their puppies, such as compassion, patience, and love!

Raised by Rhonda W.

Southern Ohio Great Danes · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friends!

DC

Raised by Debbie C.

Debbie's Pups · Meet breeder for pickup

Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.

MS

Raised by Madison S.

Madison’s Great Danes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

JT

Raised by Jen T.

Scoobz Crew Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Gregory G.

GrinerDanes · Meet breeder for pickup

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by John & Mandy W.

Weslow AKC Danes · Drop-off to you

We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.

Raised by Amanda R.

Southern Beauty Danes · Meet breeder for pickup

We're new breeders starting a small program. We hope to help provide families with quality puppies as we continue to learn & grow!

Raised by Kristen K.

2K Great Danes · Meet breeder for pickup

We offer Great Danes that fit the AKC standard for both family pets and show. They excel in obedience, therapy, and conformation!

Raised by Mark D.

River Rock Danes · Meet breeder for pickup

River Rock® Great Danes is located just SE of Columbus, OH and is breeding health tested champions and obedience titled dogs.

Raised by Kaitlin C.

Kaitlin Cunningham · Meet breeder for pickup

We strive to produce well-rounded, show-quality Great Danes that make exceptional family companions & have strong working drives.

Raised by Palmer J.

Bois D'Arc Danes · Meet breeder for pickup

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

Raised by Andrea K.

Riverwood Danes · Meet breeder for pickup

We focus on quality care and health with each litter we raise.

Raised by Pam G.

Angelwingz Kennels · Drop-off to you

We enjoy showing our dogs, & they are our companions in every adventure. We do all we can to give our dogs & pups the best lives.

Raised by Natalie A.

Lamona Great Danes · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.