40+ Great Dane puppies for sale from ethical breeders near O'Fallon, MO

Raised by Misty W.

Velocity Great Danes · 244 miles away from O'Fallon, MO

We selectively breed Black Great Danes striving to produce dogs that are healthy, well tempered and meet the Great Dane standard.

ES

Raised by Emily S.

Emily's Great Danes · 247 miles away from O'Fallon, MO

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Karie L.

Lightfoot Danes · 247 miles away from O'Fallon, MO

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

TD

Raised by Tabitha D.

Tabitha's Great Danes · 247 miles away from O'Fallon, MO

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

CS

Raised by Chris S.

Big Dog Danes · 247 miles away from O'Fallon, MO

We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.

Raised by Barbara B.

Woolf Spirit Danes · 248 miles away from O'Fallon, MO

Our program strives to breed to the breed standard. We breed for conformation, health, and temperament.

RW

Raised by Rachel W.

Limestone Farm Danes · 248 miles away from O'Fallon, MO

We offer top quality AKC Great Danes that are bred with a focus on temperament, health, and conformation.

Raised by Jodi L.

Borealis Danes · Meet breeder for pickup

I offer well-tempered, health-tested Great Danes for loving homes. They are happy, intelligent, and cute as can be!

Raised by Sonia G.

Rockingdane Great Danes · Meet breeder for pickup

I have had Great Danes since 1977. I am committed to breeding healthy Great Danes with beautiful temperaments.

Raised by Hermosa W.

Rough Diamond Danes · Drop-off to you

Our goal is produce the healthiest, most loving pets we can for your family.

Raised by Toni W.

Toni Walters · Meet breeder for pickup

We care deeply about Great Danes and have built that love and respect for the breed into every aspect of our program.

Raised by Michelle P.

Babydoll Bullies & Danes · Meet 244 miles away from O'Fallon, MO

Our Great Danes come from European Champion bloodlines. We OFA test our dams & sires

Raised by Megan T.

Megan Toeller · Meet breeder for pickup

Located in Memphis, TN, KDT Danes is a small preservation breeder with typically only 1 litter per year.

Raised by Terrie R.

Terrie Rhoden Kirkland · Meet breeder for pickup

As a responsible breeder of Great Danes, I meet Good Dog's standards for health, care, and ethical practices.

Raised by Lauren B.

Balthrop Bend Farms · Drop-off to you

We raise quality and health tested AKC English Springer Spaniels and Great Danes.

Raised by Ericka C.

Harmoni Great Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Abby E.

Mara Danes · Drop-off to you

Health tested parents OFA and Embark. LIFETIME genetic health and return contract

TC

Raised by Tamela C.

Twin Oaks Danes · Meet breeder for pickup

Having a pup in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

PB

Raised by Pamela B.

Big Paw Great Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

KB

Raised by Kayla B.

Kayla's Great Danes · Meet breeder for pickup

Our puppies are excellent representations of their breed, and we are proud to offer our high-quality puppies to loving homes.

Raised by Heather W.

Genai Great Danes · Meet breeder for pickup

Our name, Genai, means "the one whom everyone loves." We love our Danes, and we hope you will too’

Raised by Patricia R.

Trisha Self's Great Danes · Meet breeder for pickup

We breed high-quality Great Dane. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Pam G.

Great Dane Ridge · Meet breeder for pickup

I strive to produce quality puppies for families that are structurally sound, healthy, intuitive and have wonderful temperaments.

Raised by Erin S.

WZ Kennels · Drop-off to you

I focus on health, temperament, structure, & longevity. I love to create positive, lasting, relationships with my puppy families.

Raised by Valerie E.

Chicago Luvabullz · Drop-off to you

I am a french Bulldog Hobby breeder in the Chicago suburbs. Chicago Danes and Luvabullz

Raised by Carol C.

LC Blue Great Danes · Meet breeder for pickup

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

Raised by Kristen I.

Galactic Danes · Drop-off to you

All of our puppies are bred, raised, and loved indoors to produce happy, healthy pets for those seeking the best family companion!

Raised by Jordan S.

River Valley Great Danes & Miniature Schnauzers · Drop-off to you

Our mission is to raise healthy, happy, adorable puppies and connect loving families with their new best friend!

SS

Raised by Sarah S.

Trumans Great Danes · Meet breeder for pickup

We do all we can to prepare each one of our puppies to thrive in their new homes.

Raised by Rebecca A.

Acres Verdes Danes · Drop-off to you

I offer quality Great Dane puppies with a focus on health, form, and function. I believe quality is more important than quantity.

Raised by Svetlana H.

ROYAL EXCALIBUR · Drop-off to you

We understand the importance of solid foundations and health test our lines to ensure we are breeding to the standards you expect.

Raised by Jason S.

Alpine Great Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Jennifer G.

Grays Danes · Drop-off to you

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Sarka V.

Ajani's Danes · Drop-off to you

We love this breed and do everything we can to help it thrive. We give each of our dogs and puppies the best care that we can.

Raised by Lisa B.

Hough's Danes and Cavaliers · Meet breeder for pickup

We are strong advocates of proper breeding practices and run our program accordingly. We breed top-quality Cavaliers in our home.

Raised by Pamela M.

Mielnickis Danes · Meet breeder for pickup

We raise our dogs with love in our home. We have high expectations for our pups and strive to pair each one with a loving family.

HM

Raised by Hope M.

Hope's Danes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Stacy J.

Jordan Giants · Drop-off to you

Healthy, happy Great Dane pups & sweet family members.

ER

Raised by Emily R.

Emily Ramsey's Great Danes · Meet breeder for pickup

I offer top-quality Great Danes puppies with a focus on health, color, conformation, and temperament. My goal to better the breed!

Raised by Stacy L.

Phoenix's Legacy Great Danes · Meet breeder for pickup

We offer Loved, Nurtured, Puppy Cultured, Healthy AKC registed puppies.

Raised by Angela W.

Spring Creek Danes · Meet breeder for pickup

Our dogs are bred to have top qualities that all families want in their puppies, such as compassion, patience, and love!

KW

Raised by Krystal W.

Krystal’s Glam Puppies · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friend!