40+ Great Dane puppies for sale from ethical breeders near O'Fallon, MO

SH

Raised by Sarah H.

Wilder Mountain Danes · Meet breeder for pickup

Each puppy is bred, raised, and loved indoors to ensure health, happiness, and harmony at the start of its life.

Raised by Melody W.

Southwind Great Danes · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Tisha B.

Barkingham Palace Danes · Drop-off to you

We offer top-quality, loving Great Danes. Babies are born and raised in our home. Puppies are raised using the rule of 7.

Raised by Kristi A.

Northern Great Danes of Colorado & Iowa · Meet 246 miles away from O'Fallon, MO

We are an in-home Great Dane breeder focused on health, temperament, proper socialization (Puppy Culture) and nutrition!

Raised by Dusti B.

Tioli Great Danes · Drop-off to you

Striving for healthy and happy fawn and brindle Great Danes for companion and show homes.

Raised by Lori H.

Waterfront Danes · Meet breeder for pickup

I offer top-quality Great Dane puppies for families who share the same love and passion that I do for these lovely companions.

Raised by Kim T.

Thomas Family Danes · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

Raised by Sarah M.

Gentle Giants of Tennessee Great Danes · Drop-off to you

Excellent quality health tested champion bloodline European Great Danes with great health and temperament.

AM

Raised by Anna M.

Delta Danes · Meet 226 miles away from O'Fallon, MO

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

MW

Raised by Marsha W.

Walden's Great Danes · Meet breeder for pickup

We care deeply about Great Danes and breed to help ensure the health and future of these wonderful dogs.

Raised by Catherine C.

Gentle Giants · Meet breeder for pickup

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

LH

Raised by Leslie H.

Elle Great Danes · Meet breeder for pickup

Our dogs excel in the ring and as beloved companions. We are very proud of their accomplishments and those of their puppies.

Raised by Jenna G.

Myshire Danes · Meet breeder for pickup

We decided to start breeding to share the best possible puppies with excellent personalities, temperament, and most of all health!

Raised by Elizabeth S.

Iron Horse Kennel · Meet breeder for pickup

We pride ourselves on providing quality puppies with good health, conformation and temperament.

AB

Raised by Anita B.

Blue Moon Danes · Meet breeder for pickup

My priority is to ensure the health and well-being of all my dogs from birth until they leave with their forever family & beyond.

Raised by Kelsey h.

A Rowe of Danes · Meet breeder for pickup

A Rowe of Danes is a family run operation located in SW Ohio. We are devoted to our love for this breed.

KB

Raised by Kelly B.

Kelly Bennett's Great Danes · Meet breeder for pickup

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

Raised by Jane H.

Southland Farms · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

IW

Raised by Isabella W.

Wright Livestock and Farm · Meet breeder for pickup

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

SB

Raised by Sherri B.

Sherri's Great Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

JM

Raised by J M.

RyVa Danes · Meet breeder for pickup

Our dogs and pups are raised in our home and are loved as family. We strive to produce high-quality show prospects and companions.

AG

Raised by Amber G.

Guyer Great Danes · Meet breeder for pickup

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Lori B.

Chanoz Great Danes · Meet breeder for pickup

We care deeply about the Great Dane and breed to help ensure the health and future of these wonderful dogs.

Raised by Lissa M.

Creek House Great Danes · Meet breeder for pickup

We love helping people find the perfect new addition to their families and we’re proud of our reputation as reliable breeders.

Raised by Cherie L.

Bellator Danes & Mini Dachshunds · Meet breeder for pickup

We breed quality AKC Mini Dachshunds & Great Danes. They are not just pets but our family members.

Raised by Jessica B.

Bauman Great Danes · Drop-off to you

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Thomas and Melissa O.

The Greater Danes · Drop-off to you

Performance tested Great Danes bred to be a loving family companion and protector!

Raised by Sarah G.

Beaver Creek Danes · Drop-off to you

Located in the "mitten state" of Michigan, we focus on breeding Great Danes for health, temperament and longevity.

Raised by Nicole K.

Kirk’s Dane Farm · Meet breeder for pickup

We strive to produce temperamentally sound and healthy puppies with each breeding.

Raised by Janet T.

Taylor's Tails of Joy · Meet breeder for pickup

My focus is on maintaining the Great Dane standard by raising structurally sound and correct puppies with excellent temperaments.

Raised by Molly G.

Diamond Danes · Meet breeder for pickup

We believe the happiest of homes are those with a giant, cuddly, goofy Dane!

MN

Raised by Michelle N.

Mirabile Visu Danes · Meet breeder for pickup

It is our goal to help ensure the future of the Great Dane through responsibly breeding our exceptional dogs.

Raised by Emily A.

Pepper Mae Danes · Drop-off to you

A house full of love and Danes just living this life one blessing at a time!

Raised by Heather G.

Dream K9 · Drop-off to you

Having a dog in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

Raised by Autumn B.

Buck Creek Great Danes · Meet breeder for pickup

We hold ourselves to high standards for the integrity of our program. All of our puppies are socialized, nurtured, and loved.

Raised by Loupin A.

Loupin's Kennel · Meet breeder for pickup

We offer top quality pets that have been breed for focus loyalty obedience and temperament. We breed only the best family pets!!!

Raised by James C.

Sand Mountain Danes LLC · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Cassandra M.

Arpin Great Danes · Drop-off to you

Our dogs are bred to have top qualities that all families want in their puppies, such as loyalty, compassion and love!

Raised by Jessica B.

JB'S Great Danes · Meet breeder for pickup

I only have 1 breeding pair at a time, so I can truly devote my time and energy to the dogs I own and the puppies I produce.

Raised by Sabrina V.

Victory Danes · Drop-off to you

Our high-quality Great Danes are the result of extensive research and thorough care for our outstanding dogs and puppies.

Raised by Chezie S.

Simko Danes · Meet breeder for pickup

All of our Simko Danes are raised in our home with us. We pride ourselves on having well-bred, friendly, happy, & healthy puppies!

Raised by Andrea A.

Apollo's Great Danes (AGD's) · Drop-off to you

We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.