40+ Great Dane puppies for sale from ethical breeders near O'Fallon, MO
Marina, mom
Cuaron, dad
Raised by Jason D.
Legado Danes · 20 miles away from O'Fallon, MO
We breed and show top-quality dogs. Our heavy involvement in the show world speaks to the standards that we breed our dogs by.
Female, available
Female, available
Raised by Kala F.
Show Me Great Danes and Basset Hounds · 28 miles away from O'Fallon, MO
Midwest Breeder, with focus on personal relationships with adopters, puppies raised in-home, and healthy breeding practices.
1 owner review
Bijou, mom
Benelli, mom
Raised by Eleesha L.
A Spot Of Blue Great Danes/ Marshland Corgis · 35 miles away from O'Fallon, MO
We are A Spot Of Blue Great Danes/Marshland Corgis. We breed quality, health tested, Great Danes and Show prospect Pembroke Corgis
1 owner review
Raised by Joyce G.
Liberty Danes · 69 miles away from O'Fallon, MO
Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.
We’ve screened nearly every breeder in the U.S.—only 1 in 5 meet our standard for responsible breeding.
Raised by Regina A.
Weeping willow Danes · 85 miles away from O'Fallon, MO
Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.
Raised by Linda S.
Owl Valley Danes · 85 miles away from O'Fallon, MO
We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.
- KM
Raised by Karen M.
Danemark Danes · 85 miles away from O'Fallon, MO
We focus on intentional breeding so that we can produce quality puppies that are excellent representations of the standard.
Strait, dad
Roper, mom
Raised by Christina S.
Mill Iron S Great Danes · 85 miles away from O'Fallon, MO
We’re proud of the healthy, affectionate, and behaviorally well-rounded puppies we raise for other families to love!
Nova, mom
Juliet, mom
Raised by Vicki M.
Vicki's Danes and frenchies · 87 miles away from O'Fallon, MO
We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.
Female, reserved
Male, reserved
SRRaised by Stephanie R.
Reagan’s Danes · 103 miles away from O'Fallon, MO
Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.
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Duchess, mom
Duke, dad
Raised by Robert B.
Blue Dane Ridge · 119 miles away from O'Fallon, MO
We offer Great Dane puppies from our AKC registered adults about once a year. We raise these babies in our home.
1 owner review
Male, reserved
Male, reserved
Raised by Glenda T.
T3 Enchanted Forrest Danes · 129 miles away from O'Fallon, MO
We are a small scale family owned/operated European Great Dane Breeder.
Kaya, mom
Raised by Taylor R.
Double R Danes · 132 miles away from O'Fallon, MO
At Double R Danes, we are dedicated to offering quality puppies with amazing temperament, conformation, and health above all!
Dilley, dad
Reenie, mom
Raised by Danielle E.
S&D's Gentle Giants · 136 miles away from O'Fallon, MO
All of our dogs are loved as family members. We cherish our puppies from birth up until they leave our arms to snuggle into yours!
Lily, mom
Freesia, mom
Raised by CHAD W.
Weigert Danes · 139 miles away from O'Fallon, MO
We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.
PareBear, mom
Raised by Lily & Danielle M.
That Gurl K9s · 141 miles away from O'Fallon, MO
Our puppies are excellent representations of their breed, and we are proud to offer our high-quality puppies to loving homes.
- KM
Raised by Kennedy M.
Giants and Munchkins · 144 miles away from O'Fallon, MO
We focus on intentional breeding so that we can produce quality puppies that are excellent representations of the standard.
- KN
Raised by Kim N.
Nelson Great Danes · 144 miles away from O'Fallon, MO
We care deeply about the Great Dane and breed to help ensure the health and future of these wonderful dogs.
- TG
Raised by Teresa G.
Bearbond and DelightDanes · 144 miles away from O'Fallon, MO
We value responsible breeding practices and want to do our part to ensure our breeds will continue to thrive.
Duke, dad
Love, mom
JBRaised by Julia B.
Bentleys Danes · 147 miles away from O'Fallon, MO
Every puppy I raise is adored as part of our family from birth. Our puppies will complete your home, your family, and your heart!
Perdita, mom
RRDS Rollicking Karma, mom
Raised by Amber J.
RRDanes · 147 miles away from O'Fallon, MO
RR Danes breeds to better the Great Dane breed in the areas of conformation, temperament, and service dog capabilities.
Auggie, mom
Neo, dad
AARaised by Aric A.
Aric A's Great Danes · 156 miles away from O'Fallon, MO
Our pups are home-raised. We put a lot of care into socializing them so they can transition easily into their new lives.
Female, available
Raised by DAYSHA B.
Breken Great Danes · 156 miles away from O'Fallon, MO
We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.
3 owner reviews
Female, reserved
Male, reserved
Raised by Dustin & Karen M.
7Sisters Great Danes · 163 miles away from O'Fallon, MO
We value responsible breeding practices and want to do our part to ensure the Great Dane breed will continue to thrive.
Chaos, mom
Malcolm, dad
Raised by Emily P.
Phantasm Farms · 173 miles away from O'Fallon, MO
We are a small, intentional Great Dane breeder devoted to preserving the breed’s gentle nature, health, and structure.
Male, available
RPRaised by Robin P.
Robin's Great Danes · 177 miles away from O'Fallon, MO
I breed to preserve and to promote healthy breeding. Within a family setting, the dogs and puppies are part of my family.
1 owner review
Belle, mom
Raised by Genile D.
Dennison's Danes · 182 miles away from O'Fallon, MO
My focus is on maintaining the breed standard by raising structurally sound and correct puppies with correct temperments.
Asha, mom
LMRaised by Lindsay M.
Mathias Danes · 185 miles away from O'Fallon, MO
My pups are hand raised with our family and bred for temperament to make the perfect family pet.
RILEY, mom
Cadence, dad
Raised by Wendy & Mark W.
Simply Sublyme Great Danes · 190 miles away from O'Fallon, MO
We offer top-quality AKC Great Dane puppies from Championship bloodlines. Our dogs are OFA health tested.
Freyja, mom
Bruce, dad
Raised by Lila T.
Moonwater Danes · 203 miles away from O'Fallon, MO
We love to responsibly raise and train our puppies so they have the tools to be well-rounded, beloved family members.
Poppi, mom
Raised by Carol Wilber w.
Wil-Joi Great Danes · 219 miles away from O'Fallon, MO
We offer top-quality puppies and pride ourselves on always being there for our puppy people. We take great pride in our program!
avani, mom
avari, dad
Raised by yulissa p.
Great Dane Dynasty · 220 miles away from O'Fallon, MO
We understand the responsibility of purposefully breeding in order to do better for the breed and the families that love them!
Raised by Keri W.
Southern Grace Great Danes · 220 miles away from O'Fallon, MO
Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friends!
Female, available
Female, reserved
Raised by Jake W.
Bull West Kennels · 228 miles away from O'Fallon, MO
It's our goal to produce adorable, affectionate Great Dane puppies that are healthy, well-tempered, and make wonderful companions.
Male, reserved
Male, reserved
Raised by Kelly M.
Dusty Dream Danes · 233 miles away from O'Fallon, MO
We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.
Male, reserved
Raised by Jes R.
HCR Great Danes · 234 miles away from O'Fallon, MO
Our dogs are bred for health, temperament and structure. We strive to produce the best overall pets and family members.
19 owner reviews
Banana, mom
Levi, dad
Raised by Robin P.
Aidens Great Danes · 235 miles away from O'Fallon, MO
Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.
Female, reserved
Male, reserved
Raised by Bev K.
Foto Danes · 235 miles away from O'Fallon, MO
I'm a breeder with a focus on health, temperament, and soundness. I follow the guidelines of the GDCA Breeders' Code of Ethics.
Raised by Kelsey F.
K.C. Kennels · 236 miles away from O'Fallon, MO
We take great pride in breeding to produce pups that are the total package.
Lucy, mom
Bodhi, dad
Raised by Kayla L.
Oak View Danes · 238 miles away from O'Fallon, MO
We understand the responsibility of purposefully breeding in order to do better for the breed and the families that love them!
12 owner reviews
Male, reserved
Female, reserved
Raised by Michelle C.
Campbell Great Danes · 243 miles away from O'Fallon, MO
Puppies are raised in our home. They come from AKC champion bloodlines. Parent dogs are OFA tested. Puppies are AKC registered.
Crew, mom
Raised by Misty W.
Velocity Great Danes · 244 miles away from O'Fallon, MO
We selectively breed Black Great Danes striving to produce dogs that are healthy, well tempered and meet the Great Dane standard.
Related breeds
Great Dane
Buyer’s Guide
Nationally, prices usually range from $2,000 to $3,000. While it may cost more up front, starting with a healthy puppy can help you avoid costly issues later. These ranges reflect the care behind responsible breeding and offer a reliable view of what ethical breeding really costs.
About the Great Dane
This dog is magnificent, combining great size and commanding appearance with a surprising amount of gentleness and, yes, goofiness. Learn more
Moderate Energy
Energy level
Minimal Maintenance
Grooming
Average Trainability
Trainability
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Frequently asked questions
What is the average cost of Great Dane puppies in O'Fallon, MO?
Prices may vary based on the breeder and individual puppy for sale in O'Fallon, MO. On Good Dog, Great Dane puppies in O'Fallon, MO range in price from $1,500 to $2,500. We recommend speaking directly with your breeder to get a better idea of their price range.
Is Great Dane in O'Fallon, MO a high shedding breed?
Great Dane puppies in O'Fallon, MO are a moderate shedding breed. However, it's possible that a dog's level of shedding may vary by individual puppy.
How long do Great Dane puppies in O'Fallon, MO live on average?
Great Dane puppies in O'Fallon, MO may live on average between 7 to 10 years.
Do Great Dane need a lot of exercise in O'Fallon, MO?
Great Dane puppies in O'Fallon, MO tend to have moderate energy. Typically, dogs with a moderate energy level may require around 30 to 60 minutes per day of physical activity, though individual dogs may fall outside that range.
Can I adopt a Great Dane from a rescue or shelter?
On Good Dog, you can search for Great Dane puppies or dogs in rescues and shelters near O'Fallon, MO. Adopting a Great Dane from a shelter or rescue in O'Fallon, MO is generally less expensive than buying a puppy from a breeder with ethical practices. Across the United States, there are dedicated rescues that specialize in specific breeds and may even help transport a Great Dane dog to you in O'Fallon, MO from another part of the country. Although it can be more cost-effective, adopting the exact breed you're looking for is typically more difficult than working with a responsible breeder. Learn more about adopting a dog from a shelter or rescue.
About Good Dog
About Good Dog
Good Dog is your trusted partner for finding Great Dane puppies for sale near O'Fallon, MO. Our vetted network of responsible Great Dane breeders makes it easy to search listings, connect directly, and ask questions — all in one safe, protected place. Work directly with breeders you can trust and complete payments securely through Good Dog, so you can bring home your Great Dane puppy with confidence.