40+ Great Dane puppies for sale from ethical breeders near Florence, SC

Raised by Kim G.

Garrow Danes House of Blues · Drop-off to you

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

Raised by Jordan S.

River Valley Great Danes & Miniature Schnauzers · Drop-off to you

Our mission is to raise healthy, happy, adorable puppies and connect loving families with their new best friend!

Raised by Ashley M.

Halsey Danes · Drop-off to you

Our kennel is a proud home to some of the most majestic and pedigreed European Great Danes. Let’s talk!

MC

Raised by Marie C.

Marie Chambers · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

Raised by Laura H.

Boxers and Great Danes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Elizabeth Y.

KISS Great Danes · Drop-off to you

We understand the importance of solid foundations and health test our lines to ensure we are breeding to the standards you expect.

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Raised by shari s.

Shari Skory's Great Danes & Old English Sheepdogs · Meet breeder for pickup

We breed to both help ensure the future of our breeds and to improve upon our dogs' fantastic traits with each generation.

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Raised by Lindsay M.

Mathias Danes · Drop-off to you

My pups are hand raised with our family and bred for temperament to make the perfect family pet.

Raised by Jennifer G.

Grays Danes · Drop-off to you

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

MW

Raised by Marsha W.

Walden's Great Danes · Meet breeder for pickup

We care deeply about Great Danes and breed to help ensure the health and future of these wonderful dogs.

Raised by Sterling M.

Sterling Danes · Meet breeder for pickup

Breeder of black and blue Great Danes. I show in conformation, agility, obedience, and rally with my dogs. All are health tested.

Raised by Genile D.

Dennison's Danes · Drop-off to you

My focus is on maintaining the breed standard by raising structurally sound and correct puppies with correct temperments.

Raised by Julie D.

DiolaDanes · Drop-off to you

Family raised Great Danes bred for conformation and temperament. We are specializing in companions for homes with special needs.

Raised by Cassandra S.

Majestic Merles of Maine · Meet breeder for pickup

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

Raised by Christina C.

Northwood Euro Danes and Bassets · Drop-off to you

We are a small-scale breeding program with unique Great Danes. Our dogs are beautiful, healthy, well-tempered, and loved!

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Raised by Aric A.

Aric A's Great Danes · Drop-off to you

Our pups are home-raised. We put a lot of care into socializing them so they can transition easily into their new lives.

Raised by Misty W.

Velocity Great Danes · Meet breeder for pickup

We selectively breed Black Great Danes striving to produce dogs that are healthy, well tempered and meet the Great Dane standard.

Raised by Robert B.

Blue Dane Ridge · Meet breeder for pickup

We offer Great Dane puppies from our AKC registered adults about once a year. We raise these babies in our home.

Raised by Pamela M.

Mielnickis Danes · Meet breeder for pickup

We raise our dogs with love in our home. We have high expectations for our pups and strive to pair each one with a loving family.

Raised by Danielle E.

S&D's Gentle Giants · Meet breeder for pickup

All of our dogs are loved as family members. We cherish our puppies from birth up until they leave our arms to snuggle into yours!

Raised by Kenny C.

Creek Danes · Meet breeder for pickup

Our high-quality Great Danes are the result of extensive research and thorough care for our outstanding dogs and puppies.

Raised by Wendy & Mark W.

Simply Sublyme Great Danes · Meet breeder for pickup

We offer top-quality AKC Great Dane puppies from Championship bloodlines. Our dogs are OFA health tested.

Raised by CHAD W.

Weigert Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

JM

Raised by J M.

RyVa Danes · Meet breeder for pickup

Our dogs and pups are raised in our home and are loved as family. We strive to produce high-quality show prospects and companions.

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Raised by Amber G.

Guyer Great Danes · Meet breeder for pickup

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Lori B.

Chanoz Great Danes · Meet breeder for pickup

We care deeply about the Great Dane and breed to help ensure the health and future of these wonderful dogs.

Raised by Lissa M.

Creek House Great Danes · Meet breeder for pickup

We love helping people find the perfect new addition to their families and we’re proud of our reputation as reliable breeders.

Raised by Jes R.

HCR Great Danes · Drop-off to you

Our dogs are bred for health, temperament and structure. We strive to produce the best overall pets and family members.

RP

Raised by Robin P.

Robin's Great Danes · Meet breeder for pickup

I breed to preserve and to promote healthy breeding. Within a family setting, the dogs and puppies are part of my family.

Raised by Dusti B.

Tioli Great Danes · Drop-off to you

Striving for healthy and happy fawn and brindle Great Danes for companion and show homes.

Raised by Dawn T.

Teuscher Danes · Meet breeder for pickup

As a responsible breeder of Great Danes, I meet Good Dog's standards for health, care, and ethical practices.

Raised by Tori A.

Lazy A Danes · Drop-off to you

We are a small breeding program dedicated to bettering the Great Dane Breed.

Raised by Andrea H.

Not So Dainty Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Cherie L.

Bellator Danes & Mini Dachshunds · Meet breeder for pickup

We breed quality AKC Mini Dachshunds & Great Danes. They are not just pets but our family members.

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Raised by Sarah S.

Trumans Great Danes · Meet breeder for pickup

We do all we can to prepare each one of our puppies to thrive in their new homes.

Raised by Eve W.

Wil-Tor Great Danes · Meet breeder for pickup

Our pups are raised in our home and are loved as family. We strive to produce high-quality show prospects and companions.

Raised by Chezie S.

Simko Danes · Meet breeder for pickup

All of our Simko Danes are raised in our home with us. We pride ourselves on having well-bred, friendly, happy, & healthy puppies!

Raised by Bev K.

Foto Danes · Meet breeder for pickup

I'm a breeder with a focus on health, temperament, and soundness. I follow the guidelines of the GDCA Breeders' Code of Ethics.

Raised by Megan B.

Blessed By Danes · Drop-off to you

Our pups are home-raised. We put a lot of care into socializing them so they can transition easily into their new lives.

Raised by Jake W.

Bull West Kennels · Drop-off to you

It's our goal to produce adorable, affectionate Great Dane puppies that are healthy, well-tempered, and make wonderful companions.

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Raised by Emily S.

Emily's Great Danes · Meet breeder for pickup

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Karie L.

Lightfoot Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.