40+ Great Dane puppies for sale from ethical breeders near Cape Girardeau, MO

Raised by Marisa

Double Doo Ranch · Meet breeder for pickup

We love these pups! We love Great Danes, in general. Smart, loyal and loving, we know you’ll love them too!

Raised by Sandy M.

Sandy Mauck's Great Danes · Meet breeder for pickup

I produce top-quality pups that will continue to excel in their chosen field, whether that be showing, or as an active companion.

Raised by Nikki S.

Buffalo Creek Great Danes · Drop-off to you

As conscientious breeders, we are proud of the loving, smart, beautiful, and sound puppies we’re able to provide for others.

Raised by Brittney A.

Anderson Blau’s Great Danes · Drop-off to you

We strive to provide owners with healthy, socialized, and well bred puppies.

Raised by Kayla A.

Country Danes · Drop-off to you

We breed Great Danes for conformation, health, temperament, and longevity.

Raised by Heather H.

Falkor Skye Terriers · Drop-off to you

Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.

Raised by Cathy B.

Good dog breeder · Meet breeder for pickup

We breed high-quality Great Danes. Our breeding dogs are health-tested and are outstanding representations of the standard.

BM

Raised by Brenda M.

Majestic Danes · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

Raised by Jennifer N.

Newton's AKC Great Dane's · Meet breeder for pickup

We raise our dogs with love in our home. We have high expectations for our pups and strive to put each one into a loving family.

Raised by Audrey B.

Azal Great Danes · Drop-off to you

The Great Dane breed is an exceptional breed that we love and cherish.

Raised by Heather S.

DSD Danes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Lisa H.

Selah Great Danes & Chinese Cresteds · Meet breeder for pickup

The health of our dogs always comes first. We're committed to ethical breeding & a continued effort to enhance the breed standard.

Raised by shannon J.

Tarheel danes · Meet breeder for pickup

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

AA

Raised by Alyssa A.

TLC B & G KENNELZ · Meet breeder for pickup

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by Alexis M.

Virginia Great Danes · Drop-off to you

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by David B.

Creek Danes · Drop-off to you

Our Danes are health tested and AKC Champions before breeding

Raised by Daniel S.

KD Sweet Southern Danes · Drop-off to you

We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.

CB

Raised by Catherine B.

Mint Leaf Springs Farms · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

Raised by Tonya S.

Stark Danes · Drop-off to you

We breed for quality not quantity. We have standard and off colors and strive to produce better than the generation before.

Raised by Teresa P.

Rashane Danes · Meet breeder for pickup

I am dedicated to being a responsible breeder. I do everything possible to keep them healthy, exercised, and well socialized!

Raised by Sue B.

Sanctuary Great Danes · Drop-off to you

We offer top quality, loving family pets and show dogs with a focus on health and temperament.

Raised by Heather O.

Corazon Azul Great Danes · Meet breeder for pickup

We breed puppies from Grand Champion parents who are excellent representations of the breed. They are loving and intelligent!

Raised by Samantha F.

Ferguson Family Danes LLC · Drop-off to you

Welcome to Ferguson Family Danes where we connect Great Puppies with Great Families! We are a small in-home family run business.

Raised by Ryley N.

Rivercliff Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Natallia

Majestic Giants Great Danes · Meet breeder for pickup

We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.

LB

Raised by Lisa B.

Notoriety Danes · Drop-off to you

Our dogs are our passion and life. We occasionally offer puppies with excellent conformation, temperament, longevity, and health.

Raised by Courtney L.

Draggin Dobermans & Great Danes · Drop-off to you

I am a breeder with a focus on health and longevity while also striving to breed beautiful and well-rounded dogs.

Raised by Jaclyn M.

Splashed To Perfection Farms · Drop-off to you

Our dogs are raised in a loving home. We breed for excellence in health, temperament and color!

Raised by Chris B.

Blackmon Family Danes · Drop-off to you

Having a Great Dane is not like having a pet, it is a whole way of life that we love very much! Our dogs are our pride and joy!

Raised by Joan S.

Honi Vale Great Danes · Drop-off to you

Our dogs are well-socialized members of the family! They're bred for health, temperament, conformation, longevity, and structure.

MS

Raised by Megan S.

Haven Danes of Nebraska · Meet breeder for pickup

We understand the responsibility of purposefully breeding in order to do better for the breed and the families that love them!

DS

Raised by Dana S.

Black and Blue Great Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

Raised by Melonie E.

Winners Circle Kennel · Drop-off to you

We are preservation breeders of quality show, performance, and companion Australian Shepherds, Great Danes & Rhodesian Ridgebacks.

Raised by DANIELLE K.

Debonaire Danes · Drop-off to you

I love this breed and do everything I can to help it thrive. I give each of my dogs and puppies the best care that I can.

Raised by Stacie S.

Ohana Danes · Drop-off to you

I breed Danes for temperament, health and for conformation. I strive to breed a friendly, stable dog for families.

JF

Raised by Julia F.

Tar River Great Danes · Drop-off to you

We love to responsibly raise and train Great Danes so they have the tools to be well-rounded, beloved family members.

Raised by LeeAnne F.

Lotsaspots Danes · Drop-off to you

We offer top quality Great Danes from health tested parents, for pet and show.

Raised by Patricia M.

Sweet Baby Danes · Meet breeder for pickup

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Sarah A.

Outback Danes · Drop-off to you

Raising Quality, AKC Registered Great Danes from Health Tested Parents with a Splash of Color.

Raised by Jennifer D.

Days Danes · Meet breeder for pickup

We offer top quality, family pets with a focus on health and temperament.

Raised by Darrian C.

Sunkissed Danes · Meet breeder for pickup

A healthy structure and a beautiful temperament is what we aspire to bring out at Sunkissed Danes. Breeding for quality

Raised by Brittany C.

Ellenni Danes · Meet breeder for pickup

AKC Breeder of Merit GOLD. Our dogs do it all! Come take a peek! The quintessential family dog with a long lifespan & temperament.