40+ Great Dane puppies for sale from ethical breeders near Cape Girardeau, MO

Raised by Danielle E.

S&D's Gentle Giants · 222 miles away from Cape Girardeau, MO

All of our dogs are loved as family members. We cherish our puppies from birth up until they leave our arms to snuggle into yours!

Raised by Ashley D.

Painted to Perfection · 222 miles away from Cape Girardeau, MO

I'm a Good Dog-vetted breeder of Great Danes, meeting their standards for care, health testing, and ethical breeding.

Raised by Kelly M.

Dusty Dream Danes · 222 miles away from Cape Girardeau, MO

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Jenna G.

Dashing Danes · 223 miles away from Cape Girardeau, MO

We're always happy to answer questions and share our knowledge about responsible breeding.

Raised by Abby E.

Mara Danes · 226 miles away from Cape Girardeau, MO

Health tested parents OFA and Embark. LIFETIME genetic health and return contract

LH

Raised by Leslie H.

Elle Great Danes · 229 miles away from Cape Girardeau, MO

Our dogs excel in the ring and as beloved companions. We are very proud of their accomplishments and those of their puppies.

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Raised by Kim N.

Nelson Great Danes · 230 miles away from Cape Girardeau, MO

We care deeply about the Great Dane and breed to help ensure the health and future of these wonderful dogs.

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Raised by Teresa G.

Bearbond and DelightDanes · 230 miles away from Cape Girardeau, MO

We value responsible breeding practices and want to do our part to ensure our breeds will continue to thrive.

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Raised by Anita B.

Blue Moon Danes · 231 miles away from Cape Girardeau, MO

My priority is to ensure the health and well-being of all my dogs from birth until they leave with their forever family & beyond.

Raised by Sarah M.

Gentle Giants of Tennessee Great Danes · 236 miles away from Cape Girardeau, MO

Excellent quality health tested champion bloodline European Great Danes with great health and temperament.

HC

Raised by Heather C.

Heather's Noble Saints · 237 miles away from Cape Girardeau, MO

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Amber J.

RRDanes · 239 miles away from Cape Girardeau, MO

RR Danes breeds to better the Great Dane breed in the areas of conformation, temperament, and service dog capabilities.

Raised by Thomas and Melissa O.

The Greater Danes · 240 miles away from Cape Girardeau, MO

Performance tested Great Danes bred to be a loving family companion and protector!

Raised by Lily & Danielle M.

That Gurl K9s · 242 miles away from Cape Girardeau, MO

Our puppies are excellent representations of their breed, and we are proud to offer our high-quality puppies to loving homes.

Raised by Jordan S.

River Valley Great Danes & Miniature Schnauzers · 245 miles away from Cape Girardeau, MO

Our mission is to raise healthy, happy, adorable puppies and connect loving families with their new best friend!

Raised by CHAD W.

Weigert Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Jes R.

HCR Great Danes · Meet 208 miles away from Cape Girardeau, MO

Our dogs are bred for health, temperament and structure. We strive to produce the best overall pets and family members.

Raised by Sarka V.

Ajani's Danes · Drop-off to you

We love this breed and do everything we can to help it thrive. We give each of our dogs and puppies the best care that we can.

TC

Raised by Tamela C.

Twin Oaks Danes · Meet breeder for pickup

Having a pup in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

PB

Raised by Pamela B.

Big Paw Great Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

KB

Raised by Kayla B.

Kayla's Great Danes · Meet breeder for pickup

Our puppies are excellent representations of their breed, and we are proud to offer our high-quality puppies to loving homes.

Raised by yulissa p.

Great Dane Dynasty · Drop-off to you

We understand the responsibility of purposefully breeding in order to do better for the breed and the families that love them!

Raised by Dawn T.

Teuscher Danes · Meet breeder for pickup

As a responsible breeder of Great Danes, I meet Good Dog's standards for health, care, and ethical practices.

AA

Raised by Aric A.

Aric A's Great Danes · Drop-off to you

Our pups are home-raised. We put a lot of care into socializing them so they can transition easily into their new lives.

Raised by Jessica B.

JB'S Great Danes · Meet breeder for pickup

I only have 1 breeding pair at a time, so I can truly devote my time and energy to the dogs I own and the puppies I produce.

Raised by Carol Wilber w.

Wil-Joi Great Danes · Meet breeder for pickup

We offer top-quality puppies and pride ourselves on always being there for our puppy people. We take great pride in our program!

Raised by James C.

Sand Mountain Danes LLC · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Megan T.

Wild Willow Danes · Meet 242 miles away from Cape Girardeau, MO

We are a quality family Great Dane breeder prioritizing genetic health and friendly personalities.

Raised by Stacy J.

Jordan Giants · Drop-off to you

Healthy, happy Great Dane pups & sweet family members.

Raised by Loupin A.

Loupin's Kennel · Meet breeder for pickup

We offer top quality pets that have been breed for focus loyalty obedience and temperament. We breed only the best family pets!!!

Raised by Pamela M.

Mielnickis Danes · Meet breeder for pickup

We raise our dogs with love in our home. We have high expectations for our pups and strive to pair each one with a loving family.

Raised by Kalina W.

Sovereignty Woods Great Danes · Drop-off to you

We are a small home based, family style breeding program of atypical color AKC Great Danes.

KB

Raised by Kelly B.

Kelly Bennett's Great Danes · Meet breeder for pickup

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

Raised by Jane H.

Southland Farms · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

IW

Raised by Isabella W.

Wright Livestock and Farm · Meet breeder for pickup

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

SB

Raised by Sherri B.

Sherri's Great Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Tabitha M.

Pigeon Mtn. House of Danes · Meet breeder for pickup

We are breeders of high-quality, European, color pure Great Danes who love our dogs and are dedicated to providing excellence.

Raised by Catherine C.

Gentle Giants · Meet breeder for pickup

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

LM

Raised by Lindsay M.

Mathias Danes · Drop-off to you

My pups are hand raised with our family and bred for temperament to make the perfect family pet.

MW

Raised by Marsha W.

Walden's Great Danes · Meet breeder for pickup

We care deeply about Great Danes and breed to help ensure the health and future of these wonderful dogs.

Raised by Hermosa W.

Rough Diamond Danes · Drop-off to you

Our goal is produce the healthiest, most loving pets we can for your family.

RP

Raised by Robin P.

Robin's Great Danes · Meet breeder for pickup

I breed to preserve and to promote healthy breeding. Within a family setting, the dogs and puppies are part of my family.