40+ Great Dane puppies for sale from ethical breeders near Cape Girardeau, MO

Raised by Erin S.

WZ Kennels · Drop-off to you

I focus on health, temperament, structure, & longevity. I love to create positive, lasting, relationships with my puppy families.

CF

Raised by Carson F.

Caeruleum Danes · Meet breeder for pickup

We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.

Raised by Jason S.

Alpine Great Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Wendy & Mark W.

Simply Sublyme Great Danes · Meet breeder for pickup

We offer top-quality AKC Great Dane puppies from Championship bloodlines. Our dogs are OFA health tested.

SS

Raised by Sarah S.

Trumans Great Danes · Meet breeder for pickup

We do all we can to prepare each one of our puppies to thrive in their new homes.

Raised by Dusti B.

Tioli Great Danes · Drop-off to you

Striving for healthy and happy fawn and brindle Great Danes for companion and show homes.

Raised by Kaitlin C.

Kaitlin Cunningham · Meet breeder for pickup

We strive to produce well-rounded, show-quality Great Danes that make exceptional family companions & have strong working drives.

Raised by Kelsey h.

A Rowe of Danes · Meet breeder for pickup

A Rowe of Danes is a family run operation located in SW Ohio. We are devoted to our love for this breed.

Raised by Jenna G.

Myshire Danes · Meet breeder for pickup

We decided to start breeding to share the best possible puppies with excellent personalities, temperament, and most of all health!

Raised by Elizabeth S.

Iron Horse Kennel · Meet breeder for pickup

We pride ourselves on providing quality puppies with good health, conformation and temperament.

Raised by Toni W.

Toni Walters · Meet breeder for pickup

We care deeply about Great Danes and have built that love and respect for the breed into every aspect of our program.

Raised by Carol C.

LC Blue Great Danes · Meet breeder for pickup

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

Raised by Ericka C.

Harmoni Great Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Barbara B.

Woolf Spirit Danes · Drop-off to you

Our program strives to breed to the breed standard. We breed for conformation, health, and temperament.

PH

Raised by Pamela H.

House of Henry Great Danes 2 · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

Dm

Raised by Destiny m.

Moonstone Danes · Meet breeder for pickup

All of our dogs are loved as family members. We cherish our puppies from birth up until they leave our arms to snuggle into yours!

Raised by Valerie E.

Chicago Luvabullz · Drop-off to you

I am a french Bulldog Hobby breeder in the Chicago suburbs. Chicago Danes and Luvabullz

Raised by Misty W.

Velocity Great Danes · Meet breeder for pickup

We selectively breed Black Great Danes striving to produce dogs that are healthy, well tempered and meet the Great Dane standard.

Raised by Leslie W.

Leslie Woodard's Great Danes · Drop-off to you

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by Jake W.

Bull West Kennels · Meet 221 miles away from Cape Girardeau, MO

It's our goal to produce adorable, affectionate Great Dane puppies that are healthy, well-tempered, and make wonderful companions.

Raised by Cherie L.

Bellator Danes & Mini Dachshunds · Meet breeder for pickup

We breed quality AKC Mini Dachshunds & Great Danes. They are not just pets but our family members.

Raised by Autumn B.

Buck Creek Great Danes · Meet breeder for pickup

We hold ourselves to high standards for the integrity of our program. All of our puppies are socialized, nurtured, and loved.

Raised by Bob D.

Diamond Danes of Atlanta · Drop-off to you

Family-raised AKC Great Danes bred with intention, love, and purpose. Small program, big hearts & paws, raised right in our home.

Raised by Lorraine R.

VZTop Danes · Meet breeder for pickup

My focus is on maintaining the Dane breed standard by raising structurally sound & correct puppies with excellent temperaments.

Raised by Tisha B.

Barkingham Palace Danes · Drop-off to you

We offer top-quality, loving Great Danes. Babies are born and raised in our home. Puppies are raised using the rule of 7.

Raised by Bev K.

Foto Danes · Meet breeder for pickup

I'm a breeder with a focus on health, temperament, and soundness. I follow the guidelines of the GDCA Breeders' Code of Ethics.

Raised by Kaitlynn K.

Black Tie Danes and Sleek Society AHT · Drop-off to you

Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.

Raised by Jessica B.

Bauman Great Danes · Meet 249 miles away from Cape Girardeau, MO

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Lori H.

Waterfront Danes · Meet breeder for pickup

I offer top-quality Great Dane puppies for families who share the same love and passion that I do for these lovely companions.

Raised by Kim T.

Thomas Family Danes · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

Raised by Svetlana H.

ROYAL EXCALIBUR · Drop-off to you

We understand the importance of solid foundations and health test our lines to ensure we are breeding to the standards you expect.

ES

Raised by Emily S.

Emily's Great Danes · Meet breeder for pickup

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Karie L.

Lightfoot Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

TD

Raised by Tabitha D.

Tabitha's Great Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

CS

Raised by Chris S.

Big Dog Danes · Meet breeder for pickup

We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.

Raised by Stacy L.

Phoenix's Legacy Great Danes · Meet breeder for pickup

We offer Loved, Nurtured, Puppy Cultured, Healthy AKC registed puppies.

Raised by Whittney E.

Mountain Valley Farm Great Danes · Drop-off to you

Having a dog in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

Raised by Sonia G.

Rockingdane Great Danes · Meet breeder for pickup

I have had Great Danes since 1977. I am committed to breeding healthy Great Danes with beautiful temperaments.

Raised by Sydney H.

Sydney's Great Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Nicole K.

Kirk’s Dane Farm · Meet breeder for pickup

We strive to produce temperamentally sound and healthy puppies with each breeding.

Raised by Darryl P.

Stardust Danes · Meet breeder for pickup

I have been breeding top-quality Great Danes since 2013. I focus on health, pedigree, and beauty. I love my dogs and what I do!

AC

Raised by Anita C.

Anita Chapman · Drop-off to you

I breed top-quality Dane puppies to the written standard. I produce top-quality companions. Dogs transform a house into a home!