40+ Great Dane puppies for sale from ethical breeders near Cape Girardeau, MO

Raised by Elizabeth Y.

KISS Great Danes · Drop-off to you

We understand the importance of solid foundations and health test our lines to ensure we are breeding to the standards you expect.

Raised by Laura H.

Boxers and Great Danes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

ss

Raised by shari s.

Shari Skory's Great Danes & Old English Sheepdogs · Meet breeder for pickup

We breed to both help ensure the future of our breeds and to improve upon our dogs' fantastic traits with each generation.

Raised by Karmen U.

Underwood Danes AKC · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

CM

Raised by Christy M.

QC MOSS DANES · Meet breeder for pickup

Having a dog in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

Kl

Raised by Kathy l.

Kwdanes · Meet breeder for pickup

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

TM

Raised by Tiffany M.

Infinity Danes · Meet breeder for pickup

We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.

TH

Raised by Tracey H.

Bonetown Great Danes · Drop-off to you

We love to responsibly raise and train our puppies so they have the tools to be well-rounded, beloved family members.

Raised by Brittany J.

Massive Creations · Drop-off to you

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friend!

Raised by Lesa B.

Patientdanes · Meet breeder for pickup

My focus is on excellence in every aspect of my breeding program. I offer top-quality Great Dane puppies for show and pet homes.

Raised by Laura L.

Starry Night Great Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

KG

Raised by Kitty G.

KKDanes · Drop-off to you

We understand the responsibility of purposefully breeding in order to do better for the breed and the families that love them!

Raised by Melissa D.

Haltmeier-Sunrise · Drop-off to you

We breed high-quality dogs. Our breeding dogs are health-tested and are outstanding representations of the standard.

Raised by Rebecca T.

5T Danes · Drop-off to you

Family-raised Great Dane puppies focused on health, temperament, socialization, and lifelong support.

Raised by Callie T.

OnPoint Great Danes · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Corinne S.

Starlight Danes · Drop-off to you

Our Great Dane pups are home-raised. We put a lot of care into socializing them so they transition easily into their new lives.

Raised by Fay R.

Sumner Great Danes · Meet breeder for pickup

At Sumner Great Danes, we love and cherish our beloved Great Danes and strive to produce sound bodies and sound minds.

Raised by Sarah L.

Wheaton Prairie Danes-www.wpdanes.com · Drop-off to you

We are a small breeder of AKC Great Danes with a focus on healthy, happy, and sound temperaments. www.wpdanes.com

Raised by Christina C.

Northwood Euro Danes and Bassets · Drop-off to you

We are a small-scale breeding program with unique Great Danes. Our dogs are beautiful, healthy, well-tempered, and loved!

Raised by Heather G.

City Slicker Danes · Drop-off to you

We raise our dogs and puppies in our home like they are family. We live and breathe for our Danes.

Raised by Kacie H.

Scoober Danes · Drop-off to you

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Dr. Sara Rachel C.

The Nobledane · Meet breeder for pickup

I am a preservation breeder striving for quality temperament, health, and beauty of our noble breed.

TH

Raised by Terri H.

Triple D Danes · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friend!

Raised by Amber H.

Loyal-Loves Great Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Emma D.

Cowtown Danes · Drop-off to you

Health tested & Titled Parents -Our aim is to breed sport prospects and pet home puppies w/ great temperaments & on/off switches.

Raised by Becky C.

Cook’s Gentle Giants · Meet breeder for pickup

Our Great Dane pups are home-raised. We put a lot of care into socializing them so they can transition easily into their new lives

Raised by Barb B.

Symmetry Danes · Drop-off to you

We do not have puppies available at this time, however we are always happy to provide assistance or referrals to other breeders.

Raised by Misty M.

Misty Creek · Drop-off to you

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by Ann S.

Night Magic Danes · Drop-off to you

STUNNING TRAINED AKC Great Dane babies. Want to be amazed? Check out the pinned videos on our Night Magic Danes F aceBook page

Raised by Tina H.

Broken Arrow Danes · Drop-off to you

We are a small hobby breeder of Great Danes focusing on health, temperament, and conformation.

Raised by Jodie W.

Sarabi’s Pride of Danes · Drop-off to you

Small breeder but doing everything the best way possible. Using Puppy Culture and making sure they will be the best pup possible.

Raised by JC C.

Big Tex K9 Konnection · Drop-off to you

Great Dane Breeding program with imports from Europe. Focus on health and temperament. All dogs are "inside" dogs.

Raised by Wendy C.

Weco Danes · Meet breeder for pickup

Weco Danes is built upon a foundation of love, admiration, & respect for the Great Dane. We offer top-quality pups bred with love!

Raised by Lesley P.

Titanium Danes · Drop-off to you

Small hobby breeder in TX who shows in conformation (AKC) and who's goal is to produce healthy sound pets and show prospects!

Raised by Kristen K.

2K Great Danes · Meet breeder for pickup

We offer Great Danes that fit the AKC standard for both family pets and show. They excel in obedience, therapy, and conformation!

KL

Raised by Kelsey L.

Good Town Kennels · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friend!

TC

Raised by Tammy C.

Clouser's Bodacious Danes & Miniature Schnauzers · Drop-off to you

We are proud to offer our Great Dane & Mini Schnauzer puppies to loving homes! Our dogs are healthy & have great temperaments.

Raised by Natalie A.

Lamona Great Danes · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Megan C.

Nick and Megan's Danes · Drop-off to you

We offer top quality, loving family pets with focus on temperament, size, and health.

Raised by Shelly D.

Oak Bend Danes · Drop-off to you

Our dogs are family, and we love and cherish our puppies until they find forever homes.

Raised by Aumielle H.

Noctua Kennels · Drop-off to you

My dogs and puppies are family—loved fiercely and raised with care, purpose, and heart.

Raised by Julie D.

DiolaDanes · Drop-off to you

Family raised Great Danes bred for conformation and temperament. We are specializing in companions for homes with special needs.