40+ Great Dane puppies for sale from ethical breeders near Cape Girardeau, MO

JM

Raised by J M.

RyVa Danes · Meet breeder for pickup

Our dogs and pups are raised in our home and are loved as family. We strive to produce high-quality show prospects and companions.

AG

Raised by Amber G.

Guyer Great Danes · Meet breeder for pickup

We’re so excited to be able to help families experience the longtime loyalty of welcoming a new puppy into their lives!

Raised by Lori B.

Chanoz Great Danes · Meet breeder for pickup

We care deeply about the Great Dane and breed to help ensure the health and future of these wonderful dogs.

Raised by Lissa M.

Creek House Great Danes · Meet breeder for pickup

We love helping people find the perfect new addition to their families and we’re proud of our reputation as reliable breeders.

Raised by Palmer J.

Bois D'Arc Danes · Meet breeder for pickup

We are huge animal lovers and have a special place in our hearts for our dogs. We want to provide top-quality beloved companions.

Raised by Andrea K.

Riverwood Danes · Meet breeder for pickup

We focus on quality care and health with each litter we raise.

Raised by Pam G.

Angelwingz Kennels · Drop-off to you

We enjoy showing our dogs, & they are our companions in every adventure. We do all we can to give our dogs & pups the best lives.

Raised by Caitlin L.

Pawlmetto Danes · Drop-off to you

We strive to pair the best Danes, to keep our bloodline pristine and in good health!

Raised by Andrea A.

Apollo's Great Danes (AGD's) · Drop-off to you

We are proud to offer our beautiful Great Dane puppies to loving homes! Our dogs are healthy and have great temperaments.

Raised by Crystal B.

CAB Danes · Meet breeder for pickup

I am a proud breeder of Great Danes focusing on quality, health, show, and companionship. I love my dogs and what I do.

Raised by Morgan S.

LakeSide Danes · Drop-off to you

We offer top quality, loving and loyal family pets, focusing on temperament.

Raised by Kristi A.

Northern Great Danes of Colorado & Iowa · Drop-off to you

We are an in-home Great Dane breeder focused on health, temperament, proper socialization (Puppy Culture) and nutrition!

Raised by Ashley L.

Swanger Danes · Drop-off to you

We raise our dogs with love in our home. We have high expectations for our pups and strive to pair each one with a loving family.

Raised by Jennifer F.

Dynamic Danes · Drop-off to you

All of our Danes are raised indoors and are pets first. My Danes are completely health tested and stay with me after retirement.

Raised by Megan B.

Blessed By Danes · Drop-off to you

Our pups are home-raised. We put a lot of care into socializing them so they can transition easily into their new lives.

Raised by Peggy C.

Nikolodeon Danes · Drop-off to you

We offer top quality, loving family pets with a focus on health and temperament.

Raised by Sabrina V.

Victory Danes · Drop-off to you

Our high-quality Great Danes are the result of extensive research and thorough care for our outstanding dogs and puppies.

Raised by Jordan S.

Mable Danes · Drop-off to you

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

Raised by Aerica B.

Folklore Kennel · Drop-off to you

Home-based preservation breeding program focused on Beagles and Pugs. Puppies are raised in the home and placed thoughtfully.

Raised by Jamie R.

RC Ranch Great Danes And Cane Corsos · Drop-off to you

As a responsible breeder of Great Danes, I meet Good Dog's standards for health, care, and ethical practices.

Raised by Kerynn G.

Hundeity Great Danes · Drop-off to you

Hundeity Great Danes is all about raising healthy, stately grace, noble, and the most gentle giants for their beloved new family.

Raised by Micheal K.

Michael Family Danes · Meet breeder for pickup

I raise Great Danes with a focus on health, socialization, and finding the right match for every puppy.

SD

Raised by Sherry D.

Sherwood Mastiffs · Drop-off to you

We offer high-quality puppies. Our dogs are excellent representations of their breeds, and we are proud to continue their lines.

Raised by Jill G.

Windy Ridge Danes · Drop-off to you

We offer well-rounded puppies who will excel in any adventure with their new family.

LM

Raised by Lori M.

LoriDanes Great Danes · Meet breeder for pickup

I have had Great Danes for 25 years: have been involved in the AKC show world for about 10 years. 100% BRED to GDCA standards.

Raised by Kaitlyn K.

Lazuli Great Danes & Bare Necessities American Hairless Terriers · Meet 171 miles away from Cape Girardeau, MO

We offer AKC registered Great Danes and American Hairless Terriers focusing on health, temperament, conformation, and longevity.

Raised by James M.

La Rebel Danes · Drop-off to you

Breeding quality Great Dane puppies. We have a couple litters a year. We produce standard and off color puppies.

Raised by Gerald & Maggie H.

10 Acre Danes LLC · Meet 235 miles away from Cape Girardeau, MO

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

Raised by Amber B.

Bright Danes of Texas · Drop-off to you

We look so forward to meeting our Dane families and have babies all over the country! Check out our reviews on our FB page!

Raised by Amanda Y.

Danes of Dundee · Drop-off to you

We are dedicated to producing happy and health Great Dane puppies for loving and caring homes.

DC

Raised by Dave C.

Grace Redeemed Danes · Meet breeder for pickup

We work hard to produce healthy, well-rounded Great Dane puppies that will make others as happy as our dogs have made us!

Raised by Heather S.

Vegas Danes · Meet breeder for pickup

Our goal is to ensure every dog from our program is set up to live a happy and healthy life and is prepared for its future role.

RO

Raised by Rhonda O.

Heartfelt Danes · Drop-off to you

All of our puppies are bred, raised, and loved indoors to produce happy, healthy pets for those seeking the best family companion!

Raised by Tyler and Sydni B.

Garden Grove Great Danes · Drop-off to you

We strive to produce colorful danes with good structure, great health, and the best temperaments.

Raised by Laura M.

Amor Mio Great Danes · Drop-off to you

All my dogs are pets first but are capable of so much more beyond that. I train them in obedience, rally, conformation, etc.

Raised by Claudia N.

Stonebrook Gentle Giants · Drop-off to you

We focus on producing healthy puppies with outstanding temperaments. We proudly use the Puppy Culture system in our program.

Raised by Ed E.

Rocky Road Chocolate Danes · Drop-off to you

We raise adorable, affectionate, versatile puppies, and give them the best possible start for a life of companionship and love!

DG

Raised by Dana G.

Dana's Danes · Drop-off to you

Danas Danes has been breeding high quality Danes for 5 years. We have service dogs in our linage.

Raised by Krystal B.

Southern Barron Danes & Dachshunds · Drop-off to you

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Chari M.

RCM Great Danes · Drop-off to you

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

Raised by Laura R.

Ohana Great Danes of Michigan · Meet 249 miles away from Cape Girardeau, MO

We work hard to produce healthy, well-rounded Great Dane puppies that will make great family pets.

KP

Raised by Karen P.

A20 Danes · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.