40+ Great Dane puppies for sale from ethical breeders near Spartanburg, SC

Raised by Ashley L.

Swanger Danes · Drop-off to you

We raise our dogs with love in our home. We have high expectations for our pups and strive to pair each one with a loving family.

Raised by Amelia L.

Elja Danes · Drop-off to you

We love to responsibly raise and train Great Danes so they have the tools to be well-rounded, beloved family members.

Raised by Dawn & Jon C.

Chapman House of Danes · Meet breeder for pickup

We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.

TC

Raised by Tamela C.

Twin Oaks Danes · Meet breeder for pickup

Having a pup in our lives is such a blessing. We find so much fulfillment in providing that same companionship to other homes!

PB

Raised by Pamela B.

Big Paw Great Danes · Meet breeder for pickup

We are committed to always responsibly breeding with the best interest of our puppies’ health and longevity at the forefront.

Raised by Charlie P.

Charlie Plaza's Euro Great Danes · Drop-off to you

My dogs are top of the line, bred for conformation, size & health. Both dogs are full AKC registered with an outstanding pedigree

Raised by Jason S.

Alpine Great Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Heather W.

Genai Great Danes · Meet breeder for pickup

Our name, Genai, means "the one whom everyone loves." We love our Danes, and we hope you will too’

Raised by Shannon C.

Sand Dollar Danes · Meet breeder for pickup

We strive to better the breed and breed for health, temperament and confirmation.

AM

Raised by Alice Carol M.

Coquina Great Danes · Meet breeder for pickup

We built our program with care and intention in every step. We care deeply about the health and wellbeing of this breed.

Raised by Amber H.

Loyal-Loves Great Danes · Drop-off to you

We breed high-quality puppies. We love what we do and are committed to producing well-bred, healthy puppies for loving homes.

Raised by Ed E.

Rocky Road Chocolate Danes · Drop-off to you

We raise adorable, affectionate, versatile puppies, and give them the best possible start for a life of companionship and love!

Raised by Tina H.

Broken Arrow Danes · Drop-off to you

We are a small hobby breeder of Great Danes focusing on health, temperament, and conformation.

Raised by Kelsey F.

K.C. Kennels · Drop-off to you

We take great pride in breeding to produce pups that are the total package.

Raised by Laura T.

Follow My Lead Great Danes · Drop-off to you

I am a dog trainer who raises and shows Great Danes. Structure, handling, and training to support confidence, and resiliency.

Raised by Lexie C.

Chaotic Canines · Drop-off to you

Specializing in breeding healthy dogs and focusing on making the breed better.

Raised by Connie H.

Timeless Danes · Drop-off to you

We have been showing and breeding Great Danes for over 20 years.

SR

Raised by Stephanie R.

Reagan’s Danes · Drop-off to you

Our dogs are bred for health, temperament, and intelligence. We strive to produce the best overall pets and family members.

Raised by Callie D.

Unity Great Danes & Staffs · Meet breeder for pickup

Hobby breeders who show and health test our dogs. Teaching puppies to be family companions and great social breed ambassadors.

Raised by Jackie v.

VanDelft Danes · Meet breeder for pickup

Established 2012; AKC Breeder Of Merit. Black & Fawn Great Danes.

Raised by Lydia J.

Blue Mountain Great Danes LLC · Drop-off to you

Our Great Danes are the result of extensive research and thorough care for our dogs and puppies.

Raised by Michelle C.

Campbell Great Danes · Drop-off to you

Puppies are raised in our home. They come from AKC champion bloodlines. Parent dogs are OFA tested. Puppies are AKC registered.

Raised by Samantha F.

Ferguson Family Danes LLC · Drop-off to you

Welcome to Ferguson Family Danes where we connect Great Puppies with Great Families! We are a small in-home family run business.

Raised by Morgan S.

LakeSide Danes · Drop-off to you

We offer top quality, loving and loyal family pets, focusing on temperament.

Raised by Juanita K.

Misty's Puppies · Meet breeder for pickup

We raise our dogs with love in our home. We have high expectations for our pups and strive to put each one into a loving family.

Raised by Megan T.

Megan Toeller · Meet breeder for pickup

Located in Memphis, TN, KDT Danes is a small preservation breeder with typically only 1 litter per year.

Raised by Tanya B.

Tanya Bennett's Great Danes · Meet breeder for pickup

We are pet owners first and foremost. All of our puppies are raised as members of our family until they’re ready to join yours.

PH

Raised by Pamela H.

House of Henry Great Danes 2 · Meet breeder for pickup

Our dogs are our beloved companions. We care deeply about this breed and are proud to be responsible Great Dane breeders.

Dm

Raised by Destiny m.

Moonstone Danes · Meet breeder for pickup

All of our dogs are loved as family members. We cherish our puppies from birth up until they leave our arms to snuggle into yours!

Raised by Danica P.

MorningStarz Great Danes · Meet breeder for pickup

Our mission is to raise healthy, happy, adorable Great Dane puppies and connect loving families with their new best friends!

Raised by Vicki M.

Vicki's Danes and frenchies · Meet breeder for pickup

We’re devoted to ensuring there are healthy puppies for others to enjoy and we do so by responsibly growing this incredible breed.

Raised by Kara F.

Lagarda's Rose Gold · Meet breeder for pickup

I’m passionate about Great Danes and am excited to responsibly share them with the world! I offer top-quality, loving pups.

Raised by Machelle M.

M&J Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

Raised by Laura O.

Kindred Spirit Danes · Meet breeder for pickup

We breed for temperment, health, longevity, conformation, and athleticism.

Raised by Amber S.

Danes From The Crick · Meet breeder for pickup

I focus on raising Great Danes with strong health foundations, early socialization, and careful matching to new homes.

Raised by Renae C.

Luna's Danes · Meet breeder for pickup

We love this breed and the experience of having litters! Our mission is to raise pups that are set to become the best companions.

Raised by Mikayla W.

Knightwood Danes · Drop-off to you

Welcome to Knightwood Danes. Breeding has helped us share the joy of our dogs with other families and individuals.

Raised by Neil L.

Lentz Great Danes · Meet breeder for pickup

We are lifelong dog enthusiasts, and we’re excited to share our passion and purpose with others through our breeding program.

Raised by Dustin & Karen M.

7Sisters Great Danes · Drop-off to you

We value responsible breeding practices and want to do our part to ensure the Great Dane breed will continue to thrive.

Raised by Taylor R.

Double R Danes · Drop-off to you

At Double R Danes, we are dedicated to offering quality puppies with amazing temperament, conformation, and health above all!

Raised by Matt T.

Florida Danes · Meet breeder for pickup

Every puppy we raise is adored as part of our family from birth. Our puppies will complete your home, your family, and your heart!

Raised by Lori H.

Waterfront Danes · Meet breeder for pickup

I offer top-quality Great Dane puppies for families who share the same love and passion that I do for these lovely companions.